抑制幽门螺旋菌中药的初步筛选

作者	单位
王绪霖	天津医学院附属医院
缴稳玲	天津医学院附属医院
吕宗舜	天津医学院附属医院
杨恕	天津医学院附属医院
陈桂芳	天津医学院附属医院

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中文摘要:

本研究对２２６例有上消化道症状患者进行的胃镜和病理学检查，诊断为慢性胃炎和消化性溃疡。同时取胃窦粘膜做幽门螺旋菌（ＨＰ）培养，其中１３６例ＨＰ阳性（６０．１８％）。经用２００种不同性味、不同作用的单味中药做对ＨＰ的抑菌试验，结果发现其中３８种中药对ＨＰ有不同程度的抑菌作用，为慢性胃炎和消化性溃疡的临床辩证论治和清除ＨＰ提供参考。

英文摘要:

At present Helicobacter pylori(HP) was taken to be closely related to chronic atrophic gastritis and peptic ulcer.226 patients with symptoms of upper digestive tract by endoscope were examined and chronic atrophic gastritis and peptic ulcer were diagnosed.Mucous membrane from gastric antrum was taken and cultured, and found that 136 cases of 226 patients were HP positive and the rate of positiveness was 60.18%.200 kinds of Chinese herbal medicine were selected to investigate its inhibitory action on HP.Results indicated that 38 among 200 kinds of Chinese herbal medicine had inhibitory effects on HP,which provided evidence for diagnosis and treatment of chronic atrophic gastritis and peptic ulcer,also for iuhibition of HP growth.

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