| 吴瑞荣.阴虚冠心病人尿17羟皮质类固醇昼夜节律变化与脑的关系[J].,1982,(2):100-102,68 |
| 阴虚冠心病人尿17羟皮质类固醇昼夜节律变化与脑的关系 |
| The Relation between Changes of Circadian Rhythm of Urinary 17-hydroxycorticosteroids and the Brain Function in "Yin-Xu"(阴虚)Patients with Coronary Heart Disease |
| |
| DOI： |
| 中文关键词: 冠心病人 正常对照组 肾阳虚 皮质类固醇 肾阴阳两虚 阴虚火旺 肾上腺皮质功能低下 小时值 阴虚证 机能减退 |
| 英文关键词: |
| 基金项目: |
|
| Hits: 1560 |
| Download times: 1054 |
| 中文摘要: |
| 肾阳虚(阳虚偏重的肾阴阳两虚)病人肾上腺皮质功能低下的研究已为国内重视。慢性气管炎重症肾阳虚(阳虚偏重的肾阴阳两虚)者尿17羟皮质类固醇(以下简称尿17羟)白天12小时值显著下降,从而提出一个假说,认为这是脑有关部位激发下丘脑—垂体—肾上腺皮质系统(HHACS)机能减退的 |
| 英文摘要: |
| The values of diurnal,over-night and 24 hrs total urinary 17-hydroxycorticosteroids(17-OHCS)in mg/100 kg of body weight were determined for patients with CHD and male normal subjects.These values might display the functional level of the hypothalamus-hypophysis-adrenocortical system under the regulating power of circadian rhythm in relevant parts of the brain.By excluding the age-sex factor,it is discovered that compared with the normal group,there is a significant increase of the value of 24 hrs urinary 17-OHCS for the"Yin-Xu"patients in the over-night samples,rather than in the diurnal ones. These results might reflect the hyperfunction of this endocrinal system and disturbance of regulating power of circadian rhythm of the CRF-ACTH-glucocorticoids in the brain.After two months of TCM treatment resulting in the amelioration of the clinical signs and symptoms of the"Yin-Xu"patients,the abnormal values of over-night and 24hrs urinary 17-OHCS were brought to a stop.There was no obvious change in every aspect of urinary 17-OHCS values for the"Yang-Xu"(阳虚)patients before and after the treatment.The significance of the result has been discussed and a hypothesis proposed-the signs and symptoms of"Yin-Xu"syndrome of the patients might be,at least partly,a result of the imbalance of some biochemical processes involved and the decrease of inhibitory function in some parts of the brain. |
| View Full Text View/Add Comment Download reader |
