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王冠庭,矫桂穑,余家勤.慢性肝病虚证(肝阴虚、脾气虚)血中微量元素锌铜的变化及其意义[J].,1982,(3):145-146,130,131
慢性肝病虚证(肝阴虚、脾气虚)血中微量元素锌铜的变化及其意义
Changes of Blood Levels of Trace Elements Zinc and Copper in Patients with Deficiency Sydrome due to Chronic Liver Diseases and-their Significances
  
DOI:
中文关键词:  慢性肝病  脾气虚  肝阴虚  虚证  微量元素锌  湿热证  肝炎后肝硬化  慢性活动性肝炎  慢性迁延性肝炎  血吸虫病性
英文关键词:
基金项目:
Author NameAffiliation
Wang Guanting 上海第二医学院卫生学教研组 
矫桂穑 上海第二医学院卫生学教研组 
余家勤 上海第二医学院卫生学教研组 
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中文摘要:
      近年来对中医虚证理论的研究,探讨其物质基础已受到广泛重视,有从细胞水平乃至分子水平寻找阴和阳的物质基础,亦有从植物神经系统或内分泌系统的功能失调进行研究等,均为阐明虚证理论提供了一些有益的资料。本文就慢性肝病包括慢性活动性肝炎、慢性迁延性肝炎、肝炎后肝硬化及血吸虫病性肝硬化患者表现虚证—肝阴虚、脾气虚见证者,进行血中微量元素锌、铜的测定,研究其含量变化并探讨其与虚证关系。
英文摘要:
      This paper reports the changes of blood levels of trace elements zinc and copper and thier significances in patients with chronic liver diseases manifested as deficiency syndrome,including both liver Yin Xu(肝阴虚,deficiency of Yin of the liver) and spleen Qi Xu(脾气虚.deficiency of vital energy of the spleen).58 cases were studied in all,among which 38 cases were chronic liver diseases,comprising 10 cases of chronic active hepatitis,6 cases of chronic persistent hepatitis,15 cases of posthepatitic cirrhosis and 7 cases of schistosomiasis cirrhosis.All the cases were pathologically proved.20 normal persons were studied as control.The patints with chronic liver diseases were again subdivided into three groups.namely,liver Yin Xu, spleen Qi Xu and Shi Zheng(实证,excessiveness symptom-complex—the occurrence of dampness and heat). The results of study have shown that in patients with liver Yin Xu,the blood zinc level averaged 7.9 μg/g,significantly lower than the control value of 31.09 μg/g(p<0.01)The blood copper level o f these patients averaged 3.99 μg/g,which showed no sigificant difference compared with the value ofthe control group(3.07 μg/g,p>0.05).In patients with spleen Qi Xu,the blood level of zine was 13.95 μg/g,which was comparatively lower than the control group(31.09μg/g),but higher than the liver Yin Xu group(p<0.01).However,the blood level of copper averaged 7.18 μg/g,which was significantly higher than the control group (3.07μg/g,p<0.01).In the Shi Zheng group,the blood levels of zinc and copper averaged respectively 22.65 μg/g and 3.84 μg/g, which showed no statistical difference compared with the control group(p>0.05).The results obtained have shown that in patients with chronic liver diseases in groups of liver Yin Xu and spleen Qi Xu,there was marked variation in blood levels of zinc and copper,whereas there was no change in patients with Shi Zheng.
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