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寇文镕,陈在嘉,陶寿淇,白曼颐,徐义枢,姚宝康,王锦志,陆宗良,吴锡桂.益气活血途径随机分组治疗急性心肌梗塞268例疗效观察[J].,1983,(3):146-148,130
益气活血途径随机分组治疗急性心肌梗塞268例疗效观察
Clinical Effect of"Yi Qi Huo Xue"(益气活血)Medicinal Herbs in Acute Myocardial Infarction:A Randomized Controlled Study
  
DOI:
中文关键词:  急性心肌梗塞  中西医结合治疗  益气活血  随机分组  西药治疗  并发症  梗塞部位  病死率  前壁  中药治疗
英文关键词:
基金项目:
Author NameAffiliation
Kou Wenrong 中国医学科学院阜外医院 
Chen Zaijia 中国医学科学院阜外医院 
Tao Shouqi 中国医学科学院阜外医院 
白曼颐 中国医学科学院阜外医院 
徐义枢 中国医学科学院阜外医院 
姚宝康 中国医学科学院阜外医院 
王锦志 中国医学科学院阜外医院 
陆宗良 中国医学科学院阜外医院 
吴锡桂 中国医学科学院阜外医院 
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中文摘要:
      我院采用中西医结合治疗急性心肌梗塞已十余年。由于急性心肌梗塞病情复杂、影响急性期予后的因素较多,既往中药治疗的方、药及方法不统一,也缺乏对照比较,故评价其疗效较困难。为进一步探讨益气活血途径的治疗作用、本组没计随机分组对照方法进行观察,其结果如下:
英文摘要:
      A total of 268 patients with acute myocardial infarction(AMI)hospitalized within 72 hours after onset were divided into two groups:infarction of anterior wall(138 cases)and of other sites(130 cases).In each group the odd number cases were treated with combined traditional Chinese medicine(TCM)using YiQi HuoXue(YQHX)drugs and western medicine(WM)(133 cases),and even number cases were treated with WM only(135 cases).The age range,sex distribution,the time interval between onset of symptoms and hospitalization,and the incidence ofmajor complications(hypotension,cardiogenic shock,heart failure and severe arrhythmia)were very similar in both groups during admission.The YQHX drugs included Panax Ginseng,Liriope Spicata,Astragalus Membranaceus, Salvia Miltiorrhiza and Angelica Sinensis.It was administered in solution by intravenous drip in the first 7 days,and then in decoction form by oral route for 4-5 weeks.The hospital mortality of the TCM-WM groups was slightly higher than WM group(12.8%:9.6%,p>0.05),but the incidences of hypotension and congestive heart failure during the acute phase and recurrent myocardial infarction after one to two years follow-up were lower in the former,although the differences were not statistically significant(p>0.05).The results suggest that no benifit was obtained by adding the above-mentioned herbs in the treatment of AMI,but the number of cases studied was too small to warrant a definite conclusion.
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