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刘太永,王旭华,陶德明,孙启松.中草药治疗食管上皮重度增生——附95例临床资料分析[J].,1983,(5):288-289,306,260
中草药治疗食管上皮重度增生——附95例临床资料分析
Study of Medicinal Herb Therapy for Severe Epithelial Dysplasia of Esophagus
  
DOI:
中文关键词:  食管上皮  炎细胞  岩白菜  显著差异  食管癌  增生性病变  胃酸反流  阴转率  重度  细胞学变化
英文关键词:
基金项目:
Author NameAffiliation
Liu Taiyong 四川省盐亭县肿瘤防治研究所 
王旭华 四川省盐亭县肿瘤防治研究所 
陶德明 四川省盐亭县肿瘤防治研究所 
孙启松 四川省盐亭县肿瘤防治研究所 
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中文摘要:
      多年来国内随诊观察资料表明,部分食管上皮增生性病变是癌变过程中的一个不稳定的中间阶段,是一个由量变到质变的潜在过程。预防和治疗食管上皮重度增生是降低食管癌发病的重要环节。我所曾用岩白菜(Begenia purpurascens)治疗食管上皮重度增生获得一定疗效。动物
英文摘要:
      95 cases of severe epithelial dysplasia of esophagus confirmed by cytopathology in the survey of esophageal carcinoma were studied. Patients were devided into three groups,namely,group A:40 patients treated with Bergemia purpurascens,a traditional herb,for six months;group B:24 patients treated with Shah Song Drink(SSD, mixture of Sophora subprostrata,Pinus tabulaeformis,etc.),consisting of three Chinese traditional drugs combined with vitamin A for six months;group C:a control group with 31 patients. Exfoliative cytologic examinations were repeated in all patients six months later.62.5% of the patients in group A,50% in group B and 38.8% in group C showed regression to normal or mild dysplasia.there was a significant difference between group A and C(P<0.05).52.6% of patients of group A,4.5% of group B and 26.7% of group C showed complete disappearance of inflammatory cells.The difference between group A and group B was very significant(P<0.01),and that between group A and Group C was also significant (P<0.05). It seems that the effects of Bergemia purpurascens and those of SSD combined with vitamin A are about the same.But Bergemia purpurascens has better effect in symptomatic improvement and anti- inflammatory action than that of SSD in the treatment of severe epithelial dysplasia of esophagus.
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