刘太永,王旭华,陶德明,孙启松.中草药治疗食管上皮重度增生——附95例临床资料分析[J].,1983,(5):288-289,306,260 |
中草药治疗食管上皮重度增生——附95例临床资料分析 |
Study of Medicinal Herb Therapy for Severe Epithelial Dysplasia of Esophagus |
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DOI: |
中文关键词: 食管上皮 炎细胞 岩白菜 显著差异 食管癌 增生性病变 胃酸反流 阴转率 重度 细胞学变化 |
英文关键词: |
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中文摘要: |
多年来国内随诊观察资料表明,部分食管上皮增生性病变是癌变过程中的一个不稳定的中间阶段,是一个由量变到质变的潜在过程。预防和治疗食管上皮重度增生是降低食管癌发病的重要环节。我所曾用岩白菜(Begenia purpurascens)治疗食管上皮重度增生获得一定疗效。动物 |
英文摘要: |
95 cases of severe epithelial dysplasia of esophagus confirmed by cytopathology in the survey of esophageal carcinoma were studied. Patients were devided into three groups,namely,group A:40 patients treated with Bergemia purpurascens,a traditional herb,for six months;group B:24 patients treated with Shah Song Drink(SSD, mixture of Sophora subprostrata,Pinus tabulaeformis,etc.),consisting of three Chinese traditional drugs combined with vitamin A for six months;group C:a control group with 31 patients. Exfoliative cytologic examinations were repeated in all patients six months later.62.5% of the patients in group A,50% in group B and 38.8% in group C showed regression to normal or mild dysplasia.there was a significant difference between group A and C(P<0.05).52.6% of patients of group A,4.5% of group B and 26.7% of group C showed complete disappearance of inflammatory cells.The difference between group A and group B was very significant(P<0.01),and that between group A and Group C was also significant (P<0.05). It seems that the effects of Bergemia purpurascens and those of SSD combined with vitamin A are about the same.But Bergemia purpurascens has better effect in symptomatic improvement and anti- inflammatory action than that of SSD in the treatment of severe epithelial dysplasia of esophagus. |
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