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周宏奎,刘梅仙,张秀丽,洪中立,王祖来,郑飞龙.丹参对肺心病患者右心功能和血液流变性的影响[J].,1984,(4):220-221,197,219
丹参对肺心病患者右心功能和血液流变性的影响
The Effect of"Huo Xue Hua Yu"Drugs on Right Ventricular Function and Blood Rheology in Chronic Cor Pulmonale
  
DOI:
中文关键词:  慢性肺心病  血液流变性  右心功能  血液流变学指标  全血粘度  红细胞电泳  丹参注射液  感染控制  红细胞压积  血浆粘度
英文关键词:
基金项目:
Author NameAffiliation
Zhou Hongkui 宁波地区医科所 
刘梅仙 宁波地区医科所 
张秀丽 宁波地区医科所 
洪中立 宁波市第三医院 
王祖来 宁波市第三医院 
郑飞龙 宁波市第三医院 
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中文摘要:
      本文对肺心病发作期患者26例在急性感染控制后,采用丹参注射液30ml 加入10%葡萄糖500ml 内静滴,10~14天为一疗程。观察治疗前后右心功能和血液流变学的变化,结果 PEP 时间缩短,RVET 时间延长和 Q-Z 时间缩短,血液流变学五项检查均有一定程度改善,其中全血粘度和红细胞电泳改善比较明显。
英文摘要:
      Injection of RadixSalviae miltiorrhizae was given intravenously to 26 chronic cor pulmonale patients(23 men and 3 women)aged 51.2±5.4 years in average,after the subsidence of acute infection.Their right ventricular function and blood rheology were improved significantly as follows:PEP time reduced from 0.133±0.018 second to 0.118±0.017 second;RVET time increased from 0.292±0.019 second to 0.324±0.020 second;PEP/RVET ratio decreased from 0.460±0.083 to 0.395±0.084;Q-Z time reduced from 0.187±0.014 second to 0.176±0.016 second. The whole blood viscosity and red corpuscle electrophoresis were also significantly improved(P<0.05). The study shows that"Huo Xue Hua Yu"drugs or drugs with action to activate blood circulation and relieve blood stasis can increase the myocardial contraction and reduce the after load of the right ventricle.There is a positive correlation between PEP time,whole blood viscosity and red corpuscle electrophoresis.The increase of whole blood viscosity and hematocrit may increase the pulmonary arterial pressure.
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