| 苏祥扶,陆凤娟,朱秋琴.中医中药在同种异体肾移植中的应用[J].,1984,(6):342-344,323 |
| 中医中药在同种异体肾移植中的应用 |
| The Use of Chinese Herbal Drugs in Xenogenous Renal Transplantation of Homologue |
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| DOI： |
| 中文关键词: 排异反应 同种异体肾移植 免疫抑制剂 中医中药 肾移植患者 养阴活血 人参 移植肾 存活时间 不可逆性 |
| 英文关键词: |
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| 中文摘要: |
| 本文总结18例同种异体肾移植患者中西医结合治疗的临床观察结果。初步看到在使用免疫抑制剂的同时,加用养阴活血等中药,对纠正患者机体阴阳失调和长期存活似有一定好处。肾移植后用人参,对患者排异反应和存活时间均无显著影响;而肾移植前用人参的2例,移植后均出现不可逆性排异反应,提示待移植患者以不用人参为宜。 |
| 英文摘要: |
| This paper deals with the clinical data about 18 cases of xenogenous renal transplantation treated by TCM-WM from June 1978 to April 1981.These cases were divided into two groups:Group I(7 cases),in which only the immunosuppressor was used;Group Ⅱ,in which both the immunosuppressor and Chinese herbal drugs were used.The use of Chinese herbal drugs was based on the principle of treatment according to symptom-sign differentiation as well as integration of the symptom-sign differentiation with disease differentiation.The latter group was subdivided into three subgroups:Group Ⅱ A—using vitality-supporting and fetus-soothing drugs(4 cases),Group Ⅱ B—using fetus-soothing and blood-activating drugs(4 cases) and Group Ⅱ C—using Yin-nourishing and blood-activating drugs(3 cases).In comparison,the immuno- rejection and incidence of postoperative complications showed no marked difference among Group Ⅰ, Group Ⅱ A, Group Ⅱ C.The immunorejection in Group IIC was nearly the same as that in Group Ⅰ 30 days after operation.In the second month after operation,it reduced slightly.Furthermore the prednisone side effect was mild.The patients survived over 3 years.It is preliminarily considered that the use of Chinese herbal drugs in addition to the use of immunosuppressor may improve the disharmonization of organism and reduce immunorejection as well as reduce the side effect of immunosuppressor,e.g.,prednisone.All these may help prolong the survival of patients. The authors also analyse the survival periods and immunorejection in patients to whom chosen ginseng (a few of them with red ginseng)were administered.Six patients were medicated before and after operation. Comparison with those who did not use ginseng was also made.It is considered that patients after renal transplantation are in a state of high immunological inhibition.The use of ginseng at this period shows no marked influence upon immunorejection and survival period of the patients.If patients are medicated with ginseng before operation,it is unfavorable for them to control postoperative immunorejection;and what is more,super acute immunorejection may occur because of the effectiveness of ginseng in changing organic reaction.Therefore it is inappopriate to use ginseng in patients waiting for renal transplantation. |
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