| 郑德灏,王敏秀,苏平,江永年.雷公藤治疗肾小球肾炎84例临床分析[J].,1984,(10):604-606,579,580 |
| 雷公藤治疗肾小球肾炎84例临床分析 |
| Clinical Analysis of 84 Cases of Glomerulonephritis Treated with Tripterygium Wilfordii |
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| 中文关键词: 雷公藤 肾小球肾炎 慢性肾炎 肾小球肾病 抗感染药 隐匿性肾炎 临床疗效 细胞毒药物 急性肾炎 中西医结合方法 |
| 英文关键词: |
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| 中文摘要: |
| 本文报告以雷公藤为主,分别合用利尿,降压、抗感染药或激素、细胞毒药物,治疗各型肾小球肾炎84例,总有效率71.4%,近期缓解率39.3%。肾小球肾病、急性肾炎、慢性肾炎普通型及隐匿性肾炎的疗效显著。对比单用雷公藤治疗53例的疗效结果,差异无显著性。为提高雷公藤的临床疗效,坚持以雷公藤为主的中西医结合治疗方法,值得进一步的研讨。 |
| 英文摘要: |
| From April 1982 to May 1983,we treated 84 cases of different types of glomcruloncphritis with TCM- WM combined,mainly with the Chinese drug Tripterygium wilfordii.The total effective rate was 71.4% the temporary symptomatic relief rate was 39.3%. After hospitalization,the 84 patients immediately took Tripterygium wilfordii extract tablets（containing 1.5g crude drug）orally,three times a day,2 to 4 tablets each time.The course of treatment varied from 20 days to 6 months.To 55 cases with obvious dropsy,hypertension and infection,diuretic,anti-hypertensive and anti-infectious drugs were administcrcd in addilion.The total effective ratc was 70.9% Marked effects were shown in cases with acute glomerulonephritis,common type of chronic glomerulonephritis,nephrosis type and latent glomerulonephritis.22 cases treated with Tripterygium wilfordii showed little curative effect at first,but after being given additional hormone treatment,the effective rate was 79.2%.Marked curative effects were observed in this group in cases with glomerulonephropathy,common type of chronic glomerulonephritis and latent glomerulonephritis.Out of 51 cases treated with Tripterygium wilfordii and hormone conjointly,and cell poison in addition only 2 cases showed some curative effects. The side-effects of Tripterygium wilfordii:white-cell count reduction occurred in 14 cases,nausea and vomit in 13 cases,SGPT increase in 11 cases,poor appetite,abdominal pain and diarrhea in a few cases. Reduced dosage or withdrawal for a time would relieve the above-mentioned symptoms. |
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