| 陈增潭,赵伯智,张和燕,陈勇,薛福珍,蔺纪英,齐学敏,关幼波,王鸿士,刘晋生.循环免疫复合物阳性慢性肝炎115例中医治疗临床分析[J].,1985,(6):332-334,323 |
| 循环免疫复合物阳性慢性肝炎115例中医治疗临床分析 |
| Clinical Analysis of 115 Cases of Chronic Hepatitis with Circulating Immune Complexes Positive Treated by TCM |
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| 中文关键词: 循环免疫复合物 慢性肝炎 有效率 肝功能 治疗后 肝炎患者 显著差异 转阴 无变化 慢活肝 |
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| 中文摘要: |
| 肝炎血热证与 CIC 具有相关性,115例 CIC 阳性慢性肝炎血热证患者,主以凉血,兼予活血、解毒、养阴的中药复方治疗,对清除 CIC 的有效率为80.9%,消除血热的有效率为90.4%,改善肝功能的有效率为76.5%,HBsAg 连续三次阴转率为20.7%。经分析凡治疗后 CIC 阴转或下降的病例,其血热证候的消退、肝功能的改善以及 HBsAg 转阴较 CIC 无变化和上升组为优,统计学上有显著差异。 |
| 英文摘要: |
| Hepatitis with heat in the blood correlates to circulating immune complexes(CIC).115 cases of chronic hepatitis(CPH 53 cases,CAH 62 cases;HBsAg positive 92 cases,HBsAg negative 23 cases)with positive CIC and heated blood were treated with Chinese medicinal herbs mainly to cool the blood.Slight symptom patients were supplied herbs such as Rhizoma Imperatae,Paeonia suffruticosa and Radix salviae miltiorrhizae;to the serious ones were added Polygonum orientale and Lobelia chinensis;to the most serious ones were added Radix Rehmanniae, Rheum palmatum and Prunus persica.These drugs were used according to symptom differentiation of three kinds of changes as a result of the heat entering the blood namely toxin accumulating,Yin impairing and blood stagnancy. The result showed that the effective rate of CIC was 80.9%,the effective rate of heated blood symptom was 90.4%, and the effective rate of liver function was 76.5%,among which CPH was 84.9% and CAH was 69.4%.It was also found that patients with CIC cleared out had the efficiency of rehabilitating liver function 4 times higher than those with unchanged CIC after a period of treatment(the former was 65.7%,but the latter 16.7%).The group with CIC decreasing or becoming negative had an average of GPT decreasing at a range of 167.5 u—185.1 u.However the group with CIC increasing or unchanged only had GPT decreasing at a range of 25.7u—43.9u.The difference was statistically significant. After treatment 20.7% of the 92 cases with HBsAg positive changed into negative three times consecutively. Those with CIC becoming negative were 25.5% and those with CIC unchanged were 7.7%.Not a case was found with CIC-increasing group becoming HBsAg negative.The writers hold that the use of Chinese herbs for cooling the blood,nourishing Yin,activating stagnation and detoxication to treat the hepatitis patients not only facilitates the clearing out of CIC,but also helps cure hepatitis symptom,rehabilitate the liver function and change the HBsAg positive into negative.This further proves the relativity between hepatitis with heat symptom of blood and CIC. |
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