| 陈国桢.肝郁脾虚证的本质探讨[J].,1985,(12):732-735,708 |
| 肝郁脾虚证的本质探讨 |
| Study on the Nature of the Symptom-Complex "Stagnancy of the Liver and Function Deficiency of the Spleen" |
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| DOI： |
| 中文关键词: 肝郁脾虚证 植物神经功能失调 小肠吸收功能 显著差异 患者 中医辨证 药物治疗 发病学 规律性 血液流变学变化 |
| 英文关键词: |
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| 中文摘要: |
| 对肝郁脾虚患者300多例做了多方面的检测,发现植物神经功能失调,环核苷酸 cAMP/cGMP 比值降低,血浆比粘度升高。小肠吸收功能降低等规律性变化,可能是肝郁脾虚证的内在的重要发病学环节;并提示根据中医辨证结合患者体内的规律性变化考虑施治,将有助于提高临床医疗实践。 |
| 英文摘要: |
| More than 300 cases of patients suffering from the symptom-complex of stagnancy of the liver and function deficiency of the spleen(SLDS)have had a series of modern examinations.The result suggests that SLDS is a symptom-complex including several important internal changes,i.e.(1)The disturbance of autonomic nervous system:Among 226 patients with SLDS,205 cases(90.71%)showed imbalance of this system;(2)Radioimmunoassay of plasma cyclic nucleotides in 311 cases,compared with the healthy control group,showed that the ratio of cAMP/cGMP decreased significantly(P<0.001);(3)Hemorheological study of 344 cases showed that there was 50% increase of blood relative viscosity,and that electrophoretic migration time of the red blood cells prolonged,(4)281 out of 389 cases showed decreased excretion rate of xylose in urine,which indicated the malabsorption of small intestine in 72.23%,The rate of synchronous appearance of the four kinds of changes reached 65%.This is an indication of the close relationship between neurohumoral system and digestive system in SLDS;and is also an indirec indication of the close relationship between‘Liver’and‘Spleen’in traditional Chinese medicine. After treatment with Chinese drugs of"soothing the liver and strengthening the spleen",the clinical efficiency was 78.3% and the laboratory findings got markedly improved.Therefore,the authors suggest that making diagnosis and treatment by the integration of the symptoms and signs of traditional Chinese medicine and the internal pathophysiological changes will be helpful in clinical practice. |
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