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庄杰盾,廖军鲜,谢仁敷,周霭祥.河车大造丸对小鼠粒系祖细胞的影响[J].,1985,(12):742-743,709
河车大造丸对小鼠粒系祖细胞的影响
An Observation of the Granulocytic Pregenitor Cells Affected by He Che Da Zao Wan(河车大造丸)
  
DOI:
中文关键词:  河车大造丸  粒系祖细胞  小鼠  造血干细胞  扩散盒  细胞集落  受体  生理盐水  十四味建中汤  集落刺激因子
英文关键词:
基金项目:
Author NameAffiliation
Zuang Jiedun 中医研究院西苑医院血液病研究室 
廖军鲜 中医研究院西苑医院血液病研究室 
谢仁敷 中医研究院西苑医院血液病研究室 
周霭祥 中医研究院西苑医院血液病研究室 
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中文摘要:
      本文为探索河车大造丸的益肾补血作用,采用造血干细胞的培养技术,观察该药对供体小鼠粒系祖细胞(CFU-C CFU-D)的影响,同时测定该药对受体小鼠 CFU-D的作用,并以生理盐水作对照,结合中医理论略加讨论。
英文摘要:
      Aplastic anemia patients,were generally treated with prescriptions or herbs which have effects to replenish the vital energy and essence of Kidney,i,e,"Bu Shen"(补肾,tonify the kidney).He Che Da Zao Wan(HCDZW)is one of the prescription commonly used.In order to see how aplastic anemia patients have a good response to Bu Shen herbs,HCDZW was injected hypodermically to a group of mice.Normal saline was given to another group of mice as control,The bone marrow granulocytic pregenitor cells or CFU-D of the experimental group assayed by the diffusion chamber technique,were significantly greater than those of the control(P<0.01).HCDZW does affect CFU-D through some humoral factors.This observation throws light on TCM theory:"Bu Shen"promotes hemopoiesis.
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