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顾丽贞,张百舜,陈玉英,段绍瑾.复方化瘀尿石汤抗炎有效部位的研究[J].,1985,(12):747-748,709
复方化瘀尿石汤抗炎有效部位的研究
A Study on the Active Anti-Inflammatory Constituents in a Chinese Decoction for the Dissipation of Urinary Stones
  
DOI:
中文关键词:  抗炎作用  总黄酮  挥发油  有效部位  尿石汤  化学成份  复方  酚酸性成分  水提  分离部位
英文关键词:
基金项目:
Author NameAffiliation
Gu Lizhen 中医研究院广安门医院基础医学研究室 
Zhang Baishun 中医研究院广安门医院基础医学研究室 
陈玉英 中医研究院广安门医院基础医学研究室 
段绍瑾 中医研究院广安门医院基础医学研究室 
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中文摘要:
      将中药化瘀尿石汤中的挥发油和总黄酮酚酸性成分进行了分离,并以急,慢性炎症模型进行药理验证。结果表明总黄酮酚酸物和水提醇溶部位具有非常明显的抗炎作用(P<0.001),系本方抗炎活性成分(部位),挥发油的作用不明显。
英文摘要:
      The therapeutic effects of a Chinese traditional decoction Hua Yu Niao Shi Tang(化瘀尿石汤)for the dissipation of the calculus in urblogical system have been recognized and identified.This decoction is composed of 16 herbs.On the basis of qualitative analysis,main chemical compounds——volatile oils,phenolic acids and flavonoids compounds,were isolated from this decoction,and subsequently the pharmacological experiments were carried out to observe the acute and chronic inflammatory reactions in mice and rats.These laboratory experiments have been repeated with similiar results: Our laboratory results indicate that the anti-inflammatory action of the mixture of flavonoids and phenolic acids as well as the ethanol soluble components of this decoction is quite satisfactory with statistical significance, while that of the volatile oils is not remarkable.
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