| 沈自尹,胡国让,施赛珠,张玲娟,吴波水,陈伟华,陈素珍,涂灏,黄杰.温阳片预防支气管哮喘季节性发作及其原理研究[J].,1986,(1):17-20,2,3 |
| 温阳片预防支气管哮喘季节性发作及其原理研究 |
| Study on Prevention of Seasonal Attack of Bronchial Asthma with Wen Yang Tablet(温阳片)and Its Mechanism |
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| DOI： |
| 中文关键词: 季节性 支气管哮喘 温阳 小青龙汤 血清 哮喘患者 原理研究 对照组 治疗前后 显效率 |
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| 中文摘要: |
| 本文采用温阳片预防哮喘季节性发作,治疗组5批284例,显效率63.4～75.0% 对照组3批81例显效率仅18.5～22.2%(P<0.01)。免疫学研究发现温阳片能抑制血清 IgE 的季节性升高,提高抑制性 T 细胞(Ts)功能。同步观察治疗前后 Ts 和血清IgE 的相关变化,发现温阳片组 IgE 与 Ts 治疗前后差数呈明显负相关(r=-0.440,P<0.05),对照组则无明显直线相关。提示温阳片可能通过免疫调节而发挥预防作用。 |
| 英文摘要: |
| In the practice of prevention and treatment of bronchial asthma,284 asthmatics were treated in the last five years in 5 batches with Wen Yang Tablet(WYT)in contrast to 81 asthmatics treated with Xiao Qing Long Decoction(小青龙汤)in 3 batches as control.The results showed that the marked effective rates were 63.4～75.0% in the groups of WYT,significantly higher than 18.5～22.2% in the control(P<0.01).The immune study showed that the seasonal increase of serum IgE could be suppressed and the Con A-induced T suppressor(Ts)function enhanced by the treatment of WYT.Ts function and serum IgE were measuredsimultaneously.The results showed that the difference of IgE between pre-and post-treatment was significantly negative correlated with that of Ts suppressive percentage in the patients treated with WYT(r=-0.440,P<0.05),while the correlation coefficient of the difference in the controls had no significance.It indicated that WYT influenced the seasonal attack of the asthmatics probably by effecting the immune regulating system and improving the Ts function. |
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