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郑金福,周霭祥,王奎,于美兰,邓成珊,王天恩,鲁玉合,杨经敏.51例血液病血虚患者的免疫功能观察[J].,1986,(3):166-168,132
51例血液病血虚患者的免疫功能观察
Immunological Function of 51 Cases of Hematological Disorders with Deficiency of Blood Patients
  
DOI:
中文关键词:  免疫功能  急性白血病  血液病  白血病患者  血虚证  缺铁性贫血  细胞免疫  慢性再障  免疫缺陷  正常人
英文关键词:
基金项目:
Author NameAffiliation
Zheng Jinfu 中国中医研究院西苑医院血液病研究室 
周霭祥 中国中医研究院西苑医院血液病研究室 
王奎 中国中医研究院西苑医院血液病研究室 
于美兰 中国中医研究院西苑医院血液病研究室 
邓成珊 中国中医研究院西苑医院血液病研究室 
王天恩 中国中医研究院西苑医院血液病研究室 
鲁玉合 延庆中医门诊部 
杨经敏 中国中医研究院西苑医院血液病研究室 
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中文摘要:
      本文观察了51例血液病血虚患者住院后开始治疗前的巨噬细胞、T 细胞、B 细胞的免疫功能,并与正常人组进行对照。结果属于血虚的再障、急性白血病患者、多具有细胞免疫和体液免疫缺陷,但属于血虚的缺铁性贫血患者免疫功能基本正常。并讨论了免疫功能与血虚、预后的关系等。
英文摘要:
      Deficiency of blood patients usually have a remarkably lowered resistance against diseases and are susceptible to microbial infection,which is due to granulocytopenia and possibly upset of immunological function.This paper presents the results of a study of 51 cases of patients suffering from aplastic anemia,acute leukemia and iron deficiency anemia.Hemoglobin was below 9g% in all cases.Patients with aplastic anemia showed defects chiefly in lymphoblast transformation,IgG and IgA determination.Both systems of immunity were defective,but more prominant in humoral immunity.Patients of acute leukemia had defects in lymphoblast transformation,E-RFC and IgM,which was more outstanding in cellular immunity.While the immunological changes of the iron deficiency anemia patients were insignificant statistically.The therapeutic response of acute leukemia patients with higher IgM levels was more favorable than those with lower ones.
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