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杨吉成,刘静山,徐培君,徐鸿贞.刺五加多糖对白血病细胞系促诱生干扰素动力学研究[J].,1986,(4):231-233,197
刺五加多糖对白血病细胞系促诱生干扰素动力学研究
Dynamics Study of Interferon Stimulating Effect of Polysaccharide of Acanthopanax Senticosus on Leukemic Cell Culture
  
DOI:
中文关键词:  刺五加多糖  干扰素诱生  诱生干扰素  促诱生  白血病细胞系  诱生剂  动力学试验  动态曲线  效价  细胞浓度
英文关键词:
基金项目:
Author NameAffiliation
Yang Jicheng 苏州医学院微生物学教研室 
Liu Jingshan 苏州医学院微生物学教研室 
徐培君 苏州医学院微生物学教研室 
徐鸿贞 苏州医学院微生物学教研室 
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中文摘要:
      用10μg/ml 的刺五加多糖针剂对本室自建的 S801白血病细胞系进行了干扰素促诱生动力学试验。结果表明刺五加多糖促诱生干扰素动态曲线与不加刺五加多糖的常规诱生曲线均在4~16小时渐升,20~24小时达高峰,然后渐降。但在各相应时间的促诱生干扰素效价均明显比常规诱生组为高,证明刺五加多糖具有促诱生干扰素效应,其效应最佳时间在20~24小时。
英文摘要:
      The present study is an experiment in dynamics of interferon stimulating effect of 10 μg/ml polysaccharide injection of Acanthopanax senticosus on leukemic cell line established by our department, The result has shown that the dynamic curve of inducing interferon with potysaccharide of Acanthopa senticosus,as that of classical induction,is gradually rising in 4~16 hours,reaching the peak in 20~24 hours,then dropping gradually.In the same period of time the interferon titer induced by polysaccharide of Acanthopanax senticosus was found significantly higher than that of the classical induction.Thus,the polysaccharide of Acanthopanax senticosus possesses stimulating interferon effect,the most effective period of time of which is from 20 to 24 hours.
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