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陈以平,刘慰祖,沈玲妹,沈静芬,徐嵩年.中医中药治疗慢性肾功能衰竭疗效观察[J].,1986,(8):465-467,452
中医中药治疗慢性肾功能衰竭疗效观察
Treatment of Chronic Renal Failure with Traditional Chinese Medicine——Follow-up of 90 Cases
  
DOI:
中文关键词:  慢性肾功能衰竭  尿毒症  中医中药治疗  慢性肾炎  原发病  肾孟肾炎  通腑泄浊法  生存期  肾功能损害  温阳法
英文关键词:
基金项目:
Author NameAffiliation
Chen Yiping 上海龙华医院 
刘慰祖 上海龙华医院 
沈玲妹 上海龙华医院 
沈静芬 上海龙华医院 
徐嵩年 上海龙华医院 
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中文摘要:
      本文对25例慢性肾功能衰竭患者作了近期疗效比较,6例病情发展趋势之观察,以及74例肌酐在5mg 以上患者生存期的调查。本文强调了通腑泄浊在治疗尿毒症中之重要性,认为温阳法在尿毒症中不宜普遍使用,对于尿毒症引起的神经症状,用通腑泄浊法可以取效,不宜以肝风内动辨证。
英文摘要:
      This paper reports the comparative observation of short term effect,the trend of disease progress and the survival period in uremic patients with plasma creatinine over 5mg%.Patients were randomly divided into two groups,group A and B,since 1981.Patients in group A were treated with"Tong Fu Xie Zhuo"(通 腑泄浊,purgating to expel the wetness-evil);while in group B,patients were treated with"Bian Zheng Lun Zhi"(辨证论治,treat the patient according to syndrome differentiation)and"Wen Yang Huo Xue"(温阳活血 warm the Yang and promote the blood circulation).The treating course was three months.The effects of these two kinds of therapy were different,group A was significantly better than group B(P<0.01).In group A,there was marked improvement in plasma creatinine concentration and creatinine clearance(P<0.01 and 0.001 respectively). Walser pointed out that the changes in renal function could be shown by the diagram of time and the reciprocal of creatinine concentration,which was almost on a straight line,and the slope indicated the speed of change in renal function.Six patients’data were plotted and compared with Waiter’s diagram.In the follow-up of 74 patients with plasma creatinine concentration over 5mg%,the one,two and three-year survival periods were 59.7%,29.0% and 8.0% respectively.It denotes that the prognosis of chronic renal failure is really very serious. This study emphasized the importance of"Tong Fu Xie Zhuo"in the treatment of uremia,the effect of the treatment could be better and stabler with addition of"Fu Zheng"(扶正,replenish the vitality).The discussion on the adverse effect of"Wen Yang"(温阳,warm the Yang)in the treatment of uremia indicated that this remedy should not be widely used.The application of"Tong Fu Xie Zhuo",instead of"Ping Gan Xi Feng"(平肝熄风,ease the liver and remove the wind-evil),is appropriate for the treatment of neurologic symptoms in uremia.
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