| 胡婉英,张健元,唐建业,虞天锡,董跃荣,宋宝兴,唐静芬.冠心病兼血瘀证与β血栓球蛋白和血小板第Ⅳ因子的关系[J].,1987,(6):338-340,323,324 |
| 冠心病兼血瘀证与β血栓球蛋白和血小板第Ⅳ因子的关系 |
| Relationship between Levels of β Thrombogiobulin,Platelet Factor Ⅳ and Coronary Heart Disease with Blood Stasis Syndrome in TCM |
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| DOI： |
| 中文关键词: 急性心肌梗塞 冠心病患者 血瘀证 血小板激活 显著差异 健康人 陈旧性心肌梗塞 球蛋白 阳虚证 肺源性心脏病 |
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| 中文摘要: |
| 本文结果表明,冠心病组的β血栓球蛋白（βTG）和血小板第Ⅳ因子（PF4）值高于健康人组,以急性心肌梗塞更为明显。46例冠心病患者中,27例兼血瘀证的βTG和 PF4明显高于19例非血瘀证,提示冠心病的βTG 和PF4升高与血瘀证有关。急性心肌梗塞组的血瘀证发生率较非急性心肌梗塞组为高。βTG 和 PF4升高与气阴虚、气阳虚证无相关,而其他疾病组中血瘀证者的βTG 和 PF4也较非血瘀证为高。故βTG 和 PF4增高是血瘀证较为特异的指标。 |
| 英文摘要: |
| The levels of β thromboglobulin（β TG）and platelet factor Ⅳ（PF4）of 46 coronary heart disease（CHD） patients were measured.The results showed that the levels of β TG and PF4 were much higher than those of the normal control（32.20±22.75 ng/ml vs 20.4±17.2 ng/ml and 14.25±13.34 ng/ml vs 4.34±3.03 ng/ml respectively,P<0.001）.It was also revealed that the levels of β TG and PF4 were evidently elevated in 9 acute myocardial infarction（AMI）patients than in 37 old myocardial infarction （OMI）and/or anginal patients（49.94±29.62 ng/ml vs 25.87±15.26 ng/ml and 21.5±18.80 ng/ml vs 10.59±8.38 ng/ml respectively,P<0.05）.It needs to be pointed out that in 46 CHD patients,27 of them were differentiated as blood stasis（BS）syndrome in TCM,and their levels of β TG and PF4 were significantly higher than those of another 19 patients without BS syndrome（43.67±23.46 ng/ml vs 15.89±4.52 ng/ml and 20.46±14.09 ng/ml vs 5.32±4.25 ng/ml respectively,P<0.001）.It is demonstrated that elevation of β TG and PF4 in CHD patients is closely related with the BS syndrome. Furthermore,BS syndrome was differentiated in AMI group as much as 89%（8/9）,while only 51%（19/37）was found in another group,the difference was significant（P<0.05）.It also indicated that a greater proportion of BS syndrome cases accounted for the higher levels of β TG and PF4 in CHD patients. The results also confirmed that there was no relation between elevation of β TG and PF4 and Qi-Yang（气阳） deficiency or Qi-Yin（气阴）deficiency syndrome.It showed that β TG and PF4 can be used as the fairly specific parameters for the BS syndrome in TCM. |
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