| 吕国庆,戴瑞鸿,顾嘉韵,费云捷.麝香保心丸在不稳定心绞痛治疗中的作用[J].,1987,(7):405-406,388 |
| 麝香保心丸在不稳定心绞痛治疗中的作用 |
| Efficacy of the Heart Protecting Musk Pill in the Treatment of Unstable Angina Pectoris |
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| DOI： |
| 中文关键词: 不稳定心绞痛 麝香保心丸 抗心肌缺血 动态心电图监护 缺血性 王不留行 进餐 持续时间 患者 症状性 |
| 英文关键词: |
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| 中文摘要: |
| 对15例不稳定心绞痛患者进行24小时动态心电图监护,并观察麝香保心丸的疗效。结果发现,该药可明显缩短心电图缺血性 ST 段下移的持续时间,与对照药相比P<0.01,并能对抗因进餐引起的心肌缺血。 |
| 英文摘要: |
| We have observed in an earlier study that Heart Protecting Musk Pill can improve myocardial ischemia on the 12 leads ECG immediately after the administration,normalizing the echocardiographic left ventricular wall motion disturbance and improving the ischemic heart in both globular and segmental left ventricular systolic performence.The present study was designed to confirm its anti-ischemia efficacy more strictly under the Holter ECG monitering.40 episodes of the ischemic ST segment depression among 15 hospitalized patients of unstable angina pectoris were observed.The results showed that the mean duration of the ischemic ST segment change was 8±1 minutes in the medication group,18±2 minutes in the placebo group and 20±3 minutes in the non-medication group with a significant difference between the former group and the latter two groups (P<0.01).Among those meal-related ST segment ischemic changes,the level of the ST depression in the Musk Pill medication group(0.44±0.11 mm)was significantly less than that in the placebo group(1.20 ±0.10 mm)and non-medication group(1.30±0.16 mm),(P<0.01).Thus it was confirmed again the anti-ischemic efficacy of the Heart Protecting Musk Pill.Its effectiveness on the different types of angina pectoris and among the compensatory and failured pump circumstances would be studied furthermore. |
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