| 尹永诜,李恩,赵玉庸,陶静华,谢惠芬,贾晓明,赵梅,宋光耀,崔艳,常春华,李琳琳,田乃庚,马新云.滋阴补肾药对鸡佝偻病钙磷代谢的影响[J].,1987,(7):423-425,390 |
| 滋阴补肾药对鸡佝偻病钙磷代谢的影响 |
| Effects of Kidney Yin Tonic on Calcium and Phosphorus Metabolism in Rickety Chickens |
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| DOI： |
| 中文关键词: 佝偻病 钙磷代谢 滋阴补肾 血清碱性磷酸酶活性 血清钙磷 六味地黄汤 钙磷含量 给药 钙磷乘积 对照组 |
| 英文关键词: |
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| 中文摘要: |
| 实验性佝偻病雏鸡在每日滴喂六味地黄汤浓煎剂条件下,两个月内,血清钙、磷浓度均高于不给药的佝偻病鸡组;而碱性磷酸酶活性则低于不给药的佝偻病鸡组。两个月后,X 线诊断证明不给药的佝偻病组严重,患病率高达65.5%,而给药组仅为16.7%。不给药组的胫骨灰分中钙、磷含量明显低于给药组(P<0.05)。滋阴补肾药物的上述效应机理可能在于药物本身含有麦角骨化醇等天然的抗佝偻病成分,或者由于增强肾的生理功能,调节了钙磷代谢的平衡。 |
| 英文摘要: |
| 100 chickens of 7 days after birth were divided into three groups randomly:The control group(Ⅰ),the rickets group(Ⅱ),the rickety chicken treated with kidney Yin tonic"Liuwei Dihuang decoction 六味地黄汤" (Ⅲ)twice daily.All of them were fed with vitamin D-free diet.The group Ⅱ and Ⅲ were bred in darkroom except group Ⅰ.Serum calcium and phosphorus concentration and alkaline phosphatase activity were deter- mined once every two weeks.A significant reduction of mean calcium and phosphorus concentration and an increased alkaline phosphatase activity were observed in group Ⅱ in comparison with group Ⅰ and group Ⅲ in certain periods.After two months,X-ray diagnosis also showed that the incidence of severe rickets in group Ⅱ (65.5%)was higher than that in group Ⅲ(16.7%).The mean calcium contents(mg/g of dry bone weight)in tibia of the three groups were 105,92 and 97 respectively(Ⅰ/Ⅱ P<0.01,Ⅱ/Ⅲ P<0.05)and the phosphorus contents were 45,40 and 44 respectively(Ⅰ/Ⅱ P<0.01,Ⅱ/Ⅲ P<0.05).The findings indicated that the tonic lowered the incidence of severe rickets might contain some natural anti-rickets components such as ergocalciferol or enhance the function of the kidney in regulating calcium and phosphorus balance. |
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