| 王君,张德山,王桂山,于福年,郑玉清,马骥.补肾法对慢性肾炎肾病型患者免疫功能的影响[J].,1987,(12):731-733,709 |
| 补肾法对慢性肾炎肾病型患者免疫功能的影响 |
| Effect of Shenqiwan on Immunological Function in Nephrotic Syndrome of Chronic Glomerulonephritis Patients |
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| DOI： |
| 中文关键词: 慢性肾炎 补肾法 肾病型 治疗后 体液免疫功能 免疫功能紊乱 肾阴阳两虚 玫瑰花环 细胞免疫功能 刺激指数 |
| 英文关键词: |
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| 中文摘要: |
| 本文检测33例慢性肾炎肾病型患者淋巴细胞转化功能、T 淋巴细胞玫瑰花环形成率和血清 IgG 的含量,各项指标均较健康对照组低。经补肾法治疗后,患者的上述免疫指标分别由治疗前的9.68±6.97、22.20±11.64、698.56±622.70上升到28.98±14.88、31.89±15.37和1054.24±417.50,经统计学处理 P 值均<0.01,表明细胞免疫和体液免疫功能紊乱,T 细胞的功能降低可能是慢性肾炎肾病发病机理中一种重要因素,补肾法治疗可以有效地纠正免疫功能紊乱状态。 |
| 英文摘要: |
| At present,there is no satisfactory therapy for nephrotic syndrome of chronic glomerulone- phritis.The Shenqiwan(SQW)in treating this disease is an experiential method of Prof.Ma Ji in Heilongjiang province.After the treatment,5 cases were remitted completely,11 cases basical remission,15 cases partial remission and 2 cases ineffective in 33 patients.In this paper,the immunological function of these patients before and after the treatment was reported.The result showed that index of stimulation(SI)of lymphoblast transformation induced by concanavalin A(Con A,9.68±6.97),percentage of erythrocyte active rosette forming cell(Ea,22.20±11.64)and the level of IgG in serum(698.56±622.70)were lower than 30 healthy controls(36.06±17.50,32.90±10.89, 1431±280.30 respectively),P<0.01.The above indices were significantly increased after SQW therapy,as compared with the group before treatment.The differences were highly significant statistically(P<0.01).There was a similar result between the type of deficiency of Kidney Yang (阳)and of both Kidney Yin(阴)and Yang.These results suggested that there were disorders in humoral and cell-mediated immunological function in the patients.The decrease of T lymphocytes function perhaps plays an important role in the pathogenesis of the disease.The immuno- pathological mechanism in types for deficiency of Kidney Yang and of both Kidney Yin and Yang may be the same.SQW cculd effectively regulate the disturbance of immunological function in the patients. |
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