杨易灿,高战影,刘健,陈琳,吴一纯.补骨脂提取物对诱发性肺腺癌作用的实验研究[J].,1987,(12):736-737,710 |
补骨脂提取物对诱发性肺腺癌作用的实验研究 |
A Study of Psoralea corylifolia Extract Against Amino-Formal Ethylate Induced Lung Adenocarcinoma in Mice |
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中文关键词: 补骨脂提取物 小鼠肺腺癌 肺组织 肺泡上皮 对照组 增生性 免疫功能 淋巴细胞 细支气管 正常组 |
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中文摘要: |
本文采用氨基甲酸乙酯诱发小鼠肺腺癌,观察补骨脂提取物对动物诱癌前后免疫功能的变化,证明其有显著增进免疫的效果;对肺组织的支气管及肺泡上皮增生性改变发生数显著低于对照组。并对肺癌结节的病理改变和超微结构特点作了观察,肺腺癌的诱发率对照组为74.36%,补骨脂组为64.1%,环磷酰胺组为59.09%,3组之间差别不显著(P>0.05)。 |
英文摘要: |
This paper aims at investigating the anticarcinoma action of Chinese drug Psoralea corylifolia extract(contains Psoralen and isopsoralen).The preventive and therapeutic effects of Psoralea corylifolia extracts on the lung-adenocarcinoma mice which is induced by amino-formal-ethylate,was observed.The lung tissue pathologic changes,its characteristic ultrastructural alterations confirmed that Psoralea corylifolia extract markedly enhanced the immunologic function on the mice with lung cancer. |
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