| 静文英,陈亦玑,丁尚贤.原发性高血压病患者肾素—血管紧张素值与中医辨证的关系[J].,1988,(11):663-664,645 |
| 原发性高血压病患者肾素—血管紧张素值与中医辨证的关系 |
| Study on the Relationship between Plasma Renin Activity-Angiotensin Ⅱ Level and TCM Differentiation in ESsentiaL Hypertension |
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| 中文关键词: 健康人 高血压病患者 中医辨证 原发性高血压病 血管紧张素 显著性 中医分型 血浆肾素活性 实证 虚证 |
| 英文关键词: |
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| 中文摘要: |
| 对103例原发性高血压病患者和20名健康人测定了血浆 PRA 及ATⅡ浓度,并结合中医辨证进行分析。结果:(1)患者组血浆 PRA 及 ATⅡ值均低于健康人(P<0.05～0.001,卧位时除外);(2)虚证组患者基础态与激发态的 PRA 及 ATⅡ值均比健康人及实证组低(P<0.001);实证组患者两个指标值虽比健康人低,但差异无显著性意义(P>0.05)。表明不同中医分型患者可能存在不同的病理生理特点,这些特点可作为辨证分型的客观指标和治疗参考。 |
| 英文摘要: |
| The levels of plasma renin activity(PRA)and angiotensin Ⅱ(ATⅡ)were measured in 103 patients with essential hypertension and 20 normal subjects and were also analyzed by the TCM differentiation of symptoms and signs:The plasma levels of PRA and ATⅡ were measured by means of radioimmunoassay.The results showed:(1)The mean values of PRA(ng/ml/h),ATⅡ(pg/ml)in supine position of normal subjects were 0.66±0.46 and 35.95±13.72 respectively,under stimulating condition were 4.30±0.79 and 76.38±33.80 respectively.The patients with essential hypertension in supine position were 0.45±0.46 and 27.55±11.55 respectively,under stimulating condition were 1.26± 1.23 and 61.90±28.25 respectively.The mean values of PRA and ATⅡ of the patients with essential hypertension were all lower than those of the normal subjects,but the plasma levels of PRA in supine position were no significant differences(P>0.05);(2)The mean levels of PRA and ATⅡ of normal subjects were different from those patients with various kinds of essential hypertension based on TCM classification:PRA and ATⅡ in supine position in normal subject group were 0.66±0.46 and 35.95±13.72 respectively,under stimulating condition were 4.30±0.79 and 76.38±33.80 respectively; in supine position in the patients with deficiency syndromes were 0.33±0.41 and 21.44±9.37 respec- tively,under stimulating condition were 0.83±0.83 and 58.20±23.10 respectively;in supine position in the patients with excess syndrome were 0.47±0.48 and 33.06±9.93 respectively,under stimulating condition were 2.34±1.18 and 67.12±14.0 respectively.The mean values of PRA and ATⅡ of the patients with different types of TCM classification were all lower than those of the normal subjects. The plasma levels of PRA and ATⅡ of the deficiency syndrome patients in both supine position and after stimulation were all lower than those of the normal subjects and excess syndrome parients. These data may be of value in typing and treating of essential hypertension. |
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