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袁兆庄,冯景春.复方秦艽片加少量激素治疗红斑狼疮的疗效观察[J].,1989,(3):156-157,133,134
复方秦艽片加少量激素治疗红斑狼疮的疗效观察
Observation on Treatment of Systemic Lupus Erythematous with Tablet Gentiana Macrophylla Complex and Minimum Dose of Prednisone
  
DOI:
中文关键词:  系统性红斑狼疮  激素治疗  观察组  秦艽  复方  强的松  对照组  疗效比较  副作用  治疗前后
英文关键词:
基金项目:
Author NameAffiliation
Yuan Zhaozhuang 北京协和医院皮肤科 
Feng Jingchun 北京协和医院皮肤科 
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中文摘要:
      内服复方秦艽片加少量强的松治疗系统性红斑狼疮(SLE)62例为观察组,同时以单服强的松治疗 SLE19例为对照组。结果;观察组有效率为80.65%,对照组为31.58%,两组疗效比较,P<0.001。在消除症状及 LE 细胞阴转等方面,观察组均优于对照组。长期服用该药无明显副作用。
英文摘要:
      Sixty-two cases of systemic lupus erythematous(SLE)treated with Tab.Gentiana macrophylla complex 5 tablets three times per day or 10 tablets twice per day and prednisone 10~30 mg per day were reported.As controls,19 cases of SLE were treated with prednisone alone at the same time. The results showed complete remission in 86.46%(50/62)cases in the observation group and 31.57% (6/19)cases in the control group.Eight cases of SLE treated with Tab.Gentiana m.complex alone also achieved complete remission in 6 cases and improvement in 2.There was very significant statistical difference between the two groups(P<0.001).The Tab.Gentiana m.complex was more effective on the improvement of nephropathy,arthralgia,erythema and restoration of ESR,LE cells and CH50,C3 than prednisone alone.No apparant side effects of Tab.Gentiana m.complex were found in this observation.
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