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吕增春,陆志华,孙静平.氧哌嗪青霉素与复方黄芩注射液治疗老年人肺部感染的临床对照研究[J].,1990,(7):413-415,389
氧哌嗪青霉素与复方黄芩注射液治疗老年人肺部感染的临床对照研究
Clinical Comparative Study of Intravenous Piperacillin Sodium or Injection of Scutellaria Compound in Patients with Pulmonary Infection
  
DOI:
中文关键词:  肺部感染  医院内肺炎  氧哌嗪青霉素  复方黄芩注射液
英文关键词:
基金项目:
Author NameAffiliation
Lü Zengchun 中国人民解放军总医院 
陆志华 中国人民解放军总医院 
孙静平 中国人民解放军总医院 
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中文摘要:
      60例老年人肺部感染,随机分为两组,30例用复方黄苓注射液治疗,30例用氧哌嗪青霉素(对照组)治疗对照观察。结果:两组显效率分别为40%、36.7%,有效率分别为33.3%,40%,总有效率分别为73.3%和76.7%;平均体温下降天数两组分别为7.34±3.02天、7.63±5.79天;症状消失或缓解天数分别为11.67±6.75天、11.53±7.30天;白细胞降至正常分别为9.03±6.53天,10.13±6.23天;肺部阴影吸收或缩小分别为16.1±7.02天、16.1±9.88天。氧哌嗪青霉素组发现4例霉菌感染,复方黄芩注射液组未发现霉菌感染。提示复方黄芩注射液是一种有希望的抗感染制剂,值得进一步深入研究。
英文摘要:
      In this survey,60 patients with pulmonary infection (mainly nosocimial pneumonia) were divided into two groups randomly.30 patients treated by injection of Scutelleria compound and 30 patients by intravenous piperacillin sodium as control.Before treatment there was no significant difference of clinical data between two groups.The total efficacy was evaluated after treatment for one week. 40%,36.7% were marked effective in corresponding.33.3%,40% were effective and 26.7%,23% were ineffective respectively.Total effective rates were 73.3% and 76.7% in corresponding group. Temperature was averagely decreased for 7.43±3.02 and 7.63±5.79 days,symptoms disappeared or relieved for 11.67±6.75 days and 11.53±7.30 days,leucocyte decreased to normal on 9.03±6.53 days and 10.13±6.23 days,roentgenographical shadows disappeared or became smaller for 16.1±7.02 days and 16.1±9.88 days in corresponding group.There were no side-effect of the functions of liver,kidney and medulla ossium in two groups.In piperacillin sodium group,fungal infection were found in 4 of 30 patients,but there was no any case suffered from fungal infection in injection of Scutelleria compound group.It was suggested that injection on Scutelleria compound is a hopeful preparation and should be stu died furtherly.
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