| 郭宇光,谢竹藩.虚寒证、虚热证患者尿PGE2、PGF2α排出量的临床观察[J].,1990,(10):593-595,580 |
| 虚寒证、虚热证患者尿PGE2、PGF2α排出量的临床观察 |
| Clinical Observation on Urine Excretion of PGE2,PGF2α in Patients with Deficiency-Cold Syndrome and Deficiency-Heat Syndrome |
| |
| DOI： |
| 中文关键词: 虚寒证 虚热证 前列腺素 E2 前列腺素 F2α 前列腺素 E2/F2α比值 |
| 英文关键词: |
| 基金项目: |
|
| Hits: 1454 |
| Download times: 807 |
| 中文摘要: |
| 用放射免疫方法测定17例虚寒证患者、15例虚热证患者及19名健康人尿中 PGE2、PGF<sub>2α排出量的变化。结果发现:虚寒证患者尿中 PGE2排出量下降,PGF2α排出量升高,PGE2/PGF2α比值明显下降;而虚热证患者尿中 PGE2排出量升高,PGF2α无明显变化,PGE2/PGF2α比值升高。提示:PGE、PGF 与中医寒热辨证密切相关。 |
| 英文摘要: |
| The 3 hours’ urine excretion of PGE2 and PGF2α in 32 patients and 19 healthy persons were determined by RIA.According to TCM,the patients were divided into two groups:17 cases of deficiency-cold syndrome and 15 cases of deficiency-heat syndrome.The result showed that in patients with deficiency-cold syndrome,the excretion of urine PGE2 was lower than that of the normal control（P<0.05）,while the excretion of urine PGF2α higher than that of the normal control （P<0.01） and hence the PGE2/PGF2α ratio was much lower（P<0.01）;in those with deficiency-heat syndrome,the excretion of urine PGE2 was higher（p<0.01）,the excretion of urine PGF2α had no significant change （P>0.05） from the normal,and the PGE2/PGF2α ratio was higher（P<0.01）.The above result indicates a close relationship between prostaglandins and the cold and heat nature of syndromes in TCM.In connection with our previous studies that showed decreased functioning of the sympathetic-adrenomedullary system and/or increased functioning of the parasympathetic nervous system with diminished catecholamines and reduced cAMP/CGMP ratio in deficiency-cold syndrome while increased functioning of the sympathetic-adrenomedullary system with augmented cate- cholamines and cAMP in deficiency-heaL syndrome,the change of prostagtandins level can be considered as an intermediate link in the pathogenesis of syndromes different in Cold and heat nature. |
| View Full Text View/Add Comment Download reader |
|
|
|
