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唐由君,陈刚,张若英,赵东坡,李成韶.传统抗癌中成药抗急性白血病(L7212)的实验研究[J].,1990,(12):734-736,710
传统抗癌中成药抗急性白血病(L7212)的实验研究
Experimental Study on Anti-Acute Leukemia with Chinese Traditional Drugs
  
DOI:
中文关键词:  急性白血病  L7212白血病  中成药  实验研究
英文关键词:
基金项目:国家中医药管理局资助项目
Author NameAffiliation
Tang You-jun 山东中医学院附属医院 
Chen Gang 山东中医学院附属医院 
张若英 山东省中医药研究所 
赵东坡 山东省中医药研究所 
李成韶 山东省中医药研究所 
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中文摘要:
      本文应用 L7212白血病模型对传统抗癌中成药(六神丸、紫金锭、犀黄丸)进行治疗性实验研究,结果发现:传统抗癌中成药有明显的抑制和杀伤实验白血病(L7212)小鼠白血病细胞的作用(P<0.05~0.001)。该药主要作用于细胞周期的 S 期(P<0.01);具有减轻、缓解白血病细胞对肝脾浸润的作用(P<0.001),从而具有显著延长白血病小鼠生存期的作用(P<0.01~0.001)。
英文摘要:
      This paper deals with the experimental study on L7212 leukemic model of mice with Chinese medicine Liushenwan(六神丸),Zhijinding(紫金锭)and Xihuangwan(犀黄丸)for the treatment.This study proved that these drugs possessed the effect of inhibiting and killing L7212 leukemic cells of the experimental leukemic mice(P<0.05~0.001).They affected the S stage of the cell multiplication cycle time mainly(P<0.01).They could relieve the infiltration of leukemic cells in the liver and spleen of L7212 mice(P<0.001)and obviously prolong the survival time of the mice(P<0.01~0.001).
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