| 李泓,卜秦琍,胡宪蕴.原发性高血压肾素、血管紧张素 Ⅱ、醛固酮及血浆心钠素水平与辨证分型关系[J].,1991,(5):271-273,260 |
| 原发性高血压肾素、血管紧张素 Ⅱ、醛固酮及血浆心钠素水平与辨证分型关系 |
| Relationship Between TCM Differential Types and Plasma Levels of Renin, Angiotension II,Aldosterone,Atrial Natriuretic Factor in Patients with Essential Hypertension |
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| DOI： |
| 中文关键词: 高血压病 中医分型 肾素 血管紧张素 心钠素 |
| 英文关键词:hypertension differential types of traditional Chinese medicine renin angiotension Ⅱ atrial natriuretic factor |
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| 中文摘要: |
| 对130例高血压病患者及70名健康人的肾素(PRA)、血管紧张素Ⅱ(ATⅡ)、醛固酮及血浆心钠素(ANP)水平的检测及对其与中医辨证分型关系进行探讨。结果表明:(1)高血压患者基础 PRA 值低于健康人,而各型组间差异较大;阳亢型组 PRA、ATⅡ明显高于对照组和阴虚阳亢、阴阳两虚组,组间差异非常显著(P<0.01～0.001)。说明PRA 及 ATⅡ在高血压中医分型中,可以作为区别各证型不同病理生理变化的客观指标之一。(2)高血压病患者 ANP 明显低于健康人(P<0.01),但三个中医证型组间无差异(P>0.05)。(3)对高血压患者严重心脑并发症的发生与中医证型及 PRA 水平的关系,各证型间转化与 PRA 水平关系作了初步探讨。 |
| 英文摘要: |
| 130 cases of patients with essential hypertension(EH)and 70 cases of normal subjects were researched for correlation between TCM differential types and plasma levels of renin,angiotension Ⅱ,aldosterone,atrial natriuretic factor(ANF)in patients with EH.Results indicated that:(1)basic level of reain was lower in patients with EH than that in normal subject.There were significant differences of plasma levels of renin between different TCM types.Plasma renin level of excessive Yang(阳)patients was higher than that in normal subject group and groups of deficiency of Yin(阴) essence combined with excessive Yang as well as deficiency of both Yin and Yang(P<0.01～0.001). Plasma level of angiotension Ⅱ was significantly higher in group of excessive Yang than that in normal subject and other two groups(P<0.01～0.001).It was indicated that there were correlation between plasma basic level of renin,angiotension Ⅱ and TCM types.(2)Plasma ANF level in patients with EH was significantly lower than that in group of normal subject(P<0.01).There were significant differences between groups of three different TCM types(P>0.05).The result suggested that lower plasma ANF level was general character in three groups with EH.The prognosis of these patientswas discussed. |
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