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庄学煊,李长潮,陈少如.当归注射液对大鼠心肌缺血再灌注时心律失常的保护作用[J].,1991,(6):360-361,326
当归注射液对大鼠心肌缺血再灌注时心律失常的保护作用
The Protective Effect of Angelica Injection on Arrhythmia during Myocardial Ischemia Reperfusion in Rat
  
DOI:
中文关键词:  当归注射液  异搏定  心肌缺血  再灌注  大鼠
英文关键词:Angelica  Verapamil  myocardial ischemia  reperfusion  rat
基金项目:
Author NameAffiliation
Zhuang Xue-xuan 汕头大学医学院病理生理教研室 (广东515031) 
李长潮 汕头大学医学院病理生理教研室 (广东515031) 
陈少如 汕头大学医学院病理生理教研室 (广东515031) 
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中文摘要:
      本文以大鼠心肌缺血再灌注为模型,研究当归注射液对再灌性心律失常的保护作用。结果表明,当归注射液腹腔注射(0.6g 生药/kg)能使室性早搏发生率和心律失常总发生率明显减少,与生理盐水对照组比较,差异显著(P<0.05),而与异搏定组比较则差异不显著。提示当归注射液对大鼠心肌缺血再灌注的心律失常具有保护作用。
英文摘要:
      protective effects of Angelica injection on the reperfusic arrhythmia were studied through the model of ischemic myocardial reperfusion in rats.The results showed that the incidence of ventrictflar premature beat and the total incidence of arrhythmia(IA)were greatly reduced bY peritoneal injection of Angelica (0.6 gm crude drug/kg) in rats.The difference between the Angelica group (n=12,IA=41.7%)and the saline control group (n=12,IA=91.7%)was significant(P<0.05), while that between Angelica group and verapamiI group (n=10,IA=40%) was insignificant (P>0. 05).The data suggested that Angelica injection is effective on the protection of arrhythmia during the myocardial ischemia reperfusion in rats.
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