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董永绥,黄志华,吴兰芬,张明.茵栀黄注射液治疗婴儿肝炎综合征机理探讨[J].,1992,(1):26-27,5,6
茵栀黄注射液治疗婴儿肝炎综合征机理探讨
Study on the Treatment of Infantile Hepatitis Syndrome with Injection of Yin Zhi Huang(茵栀黄)
  
DOI:
中文关键词:  菌栀黄注射液  婴儿肝炎综合征  T细胞亚群
英文关键词:infantile hepatitis syndrome  injection of Yin Zhi Huang  T cell subsets
基金项目:
Author NameAffiliation
Dong Yong-sui 同济医科大学附属同济医院儿科教研室 (武汉430030) 
Huang Zhi-hua 同济医科大学附属同济医院儿科教研室 (武汉430030) 
Wu Lang-fen 同济医科大学附属同济医院儿科教研室 (武汉430030) 
张明 同济医科大学附属同济医院儿科教研室 (武汉430030) 
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中文摘要:
      观察茵栀黄注射液治疗婴儿肝炎综合征前后的血清胆红素浓度、丙氨酸转氨酶(SALT)、肝脏大小,并对部分患儿检测了外周血中T细胞亚群和十二指肠液中胆红素浓度。结果表明,茵栀黄注射液有显著的退黄作用,并能使肿大的肝脏缩小,而对细胞免疫障碍无调节作用。
英文摘要:
      The infantile hepatitis syndrome is defined as a.liver disease which occurs during the infantile period with the clinical manifestation of jaundice, hepatomegaly and hepatic dysfunction. The cause of disease is complex and the treatment is difficult. From March 1987 to June 1988, 55 patients (treatment group) were treated with injection of Yin Zhi Huang, and 15 cases (control group) with injection of Inosine, vitamin C and glucose. The course of treatment lasted 15 days. At the beginning and the end of the treatment, serum bilirubin level, sALT level, duodenal juice bilirubin level, liver size and T cell subsets in peripheral blood had been detected separately. The results showed that among the treatment group, serum bilirubin level was significantly lower at the end of the treatment than that of the control group. The sALT, and hepatomegaly were also reduced or lessened, while the duodenal juice bilirubin level was increased. But there was no difference in T cell subsets between the two groups.
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