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陈可冀,李春生,张国玺,裴静琛,童伯伦,林求诚,陈文发,关斌,陈维泽.御制平安丹治疗晕动病的临床和实验研究[J].,1992,(8):469-472,452
御制平安丹治疗晕动病的临床和实验研究
Clinical and Experimental Studies of Royal Made Ping An Dan on Treatment of Motion Sickness
  
DOI:
中文关键词:  晕动病  眼震  微循环  御制平安丹
英文关键词:motion sickness  eyeball tremor  microcirculation  Royal Made Ping An Dan
基金项目:
Author NameAffiliation
Chen Ke-ji 中国中医研究院西苑医院 
Li Chun-sheng 中国中医研究院西苑医院 
Zhang Guo-xi 中国中医研究院西苑医院 
裴静琛 航天医学工程研究所 
童伯伦 航天医学工程研究所 
林求诚 福建省中医药研究所 
陈文发 福建省中医药研究所 
关斌 厦门中药厂 
陈维泽 福建省金鸡山工人温泉疗养院 
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中文摘要:
      用御制平安丹(下称平安丹)治疗晕动病(运动病)343例,观察结果表明,平安丹服后有效率为92.8%,优于乘晕宁和人丹组(P<0.05~0.01)。平安丹可影响猫前庭感受器,抑制旋转后眼震,起到调节前庭—植物性神经功能的作用;它还能改善动物软脑膜微循环,有助于调整椎基底动脉、前庭通路等区域微循环障碍。以上效果与治疗剂量东莨菪碱(Scopolamine)相似。
英文摘要:
      This paper presents the results of clinical observation and experimental research of Royal Made Ping An Dan (RPAD) of the Imperial Hospital of Qing Dynasty. The clinical results showed that RPAD was effective in treating 343 patients with motion sickness, and their average time for producing effect was 24.1 ± 13.5 minutes. The total effective rates of dramamine group and Ren Dan(人丹) group were 69.4% and 67.7% respectively, the Iatter included 45.7% of basically cured and 55.0% of markedly effective cases. There were significant differences among these groups (P<0.05--0.01). It revealed that the effect of RPAD was better than that of dramamine and Ren Dan. According to laboratory findings, RPAD had the ability of alleviating symptoms of motion sickness and inhibiting eyeball tremor and improving meningeal microcirculation of experimental animals.
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