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张华严,郁雪中,王弓力.补肾治疗黄体期功能不足的初步探讨[J].,1992,(8):473-474,452,453
补肾治疗黄体期功能不足的初步探讨
Preliminary Report on Treatment of Luteal Phase Defect by Replenishing Kidney—An Analysis of 53 cases
  
DOI:
中文关键词:  黄体期功能不足  中药  补肾法
英文关键词:luteal phase defect  replenishing the Kidney  Chinese medicinal herbs
基金项目:
Author NameAffiliation
Zhang Hua-yan 第四军医大学西京医院妇产科 西安 710032 
Yu Xue-zhong 第四军医大学西京医院妇产科 西安 710032 
Wang Gong-li 第四军医大学西京医院妇产科 西安 710032 
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中文摘要:
      对53例黄体期功能不足患者,采用中药补肾法,治疗3个月经周期,观察治疗前后子宫内膜、血清内分泌激素及基础体温,发现治疗后的内膜时相得到改善,黄体中期血清黄体生成激素(LH)及泌乳素(PRL)较治疗前下降(P<0.05),孕酮(P)明显上升(P<0.01),两组有显著性差异。53例中,22例受孕(41.51%),并观察到经补肾治疗而受孕者,部分病例易发生流产,大多数需采取保胎措施。
英文摘要:
      53 patients with Luteal phase defect (LPD) were treated with different Chinese medicinal herbs at different phases of menstrual cycle. On the 5th day of the menstrual cycle, the treatment was implemented with the rationale of "nourishing the Kidney Yin, invigorating the Spleen and raplenishing the Qi, promoting the blood circulation and enriching the Blood" which might promote follicular development. The principle for the postovulatory treatment was that "invigorating the Kidney and strengthening the Yang" might enhance the development of corpus luteum and maintain its function.The patients were treated for three menstrual cycles. There were significant improvement in theluteal phase of endometrium, and prolonged basal body temperature elevation in progestational stage with a tendency for normalization of the wave forms and its amplitude after the treatment. In the mid-progestational stage, the level of serum LH and PRL were reduced (P<0.05) and that of serum progestin (P) rose significantly (P<0.01), as compared with those before the treatment. The findings suggested that Chinese herbal medicines capable of replenishing the kidney could regulate the hypothalamus-pituitary-ovarian axis and thus improve the Iuteal function. Among the 53 cases,22 (41.5%) conceived but 68.18% of them required other measures to preserve the pregnancy.
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