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曾小澜,李心爱,章碧玉,马克荣,尹毅,麦羡霞,牛玉中,王鹤皋,叶美珍.潞党参对癌症放疗患者免疫功能和造血功能保护作用的观察[J].,1992,(10):607-608,581
潞党参对癌症放疗患者免疫功能和造血功能保护作用的观察
Immunological and Hematopoietic Effect of Codonopsis Pilosula on Cancer Patients during Radiotherapy
  
DOI:
中文关键词:  潞党参  癌症  放射治疗  免疫功能  造血功能
英文关键词:Codonopsis pilosula  immunological function  cancer  radiotherapy
基金项目:
Author NameAffiliation
Zeng Xiao-lan 山西省肿瘤研究所 
Li Xin-ai 山西省肿瘤研究所 
Zhang Bi-yu 山西省肿瘤研究所 
马克荣 山西省肿瘤研究所 
尹毅 山西省肿瘤研究所 
麦羡霞 山西省肿瘤研究所 
牛玉中 山西省肿瘤医院 
王鹤皋 山西省肿瘤医院 
叶美珍 山西省医药研究所 
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中文摘要:
      对放疗的33例肺癌、32例食管癌患者应用潞党参膏作为辅助治疗,并以单纯放疗的36例肺癌、70例食管癌患者作为对照,观察潞党参对放疗患者免疫功能及造血功能的保护作用。结果表明:潞党参对放疗患者的血红蛋白无明显作用,也未能减少放疗对白细胞的杀伤作用;但在一定程度上减少了放疗对多种细胞免疫功能(OT、PHA皮肤迟发超敏反应,淋巴细胞转化,IL-2诱导反应)及IgM的损伤,对其他体液免疫指标IgG、IgA及C3无明显影响。
英文摘要:
      Codonopsis pilosula was used as an adjuvant in 76 cancer patients during radiotherapy, and itsprotective effect on hematopoietic and immunologic function was studied. Results: (1) No influence onHb and WBC of the patients with radiotherapy. (2) It could reduce the immunosuppressive effect ofradiotherapy on delayed hypersensitive reaction, the lymphocyte response to PHA and IL-2. (3) Nodifference between treated and control groups in most humoral immune indices such as IgG, IgA andC3, but had slight increase in IgM in treated patients, while significant decrease in control.
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