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韩明向,王亿平.复肾汤对慢性肾炎脾肾阳虚型患者甲状腺激素的影响[J].,1993,(3):155-157,133
复肾汤对慢性肾炎脾肾阳虚型患者甲状腺激素的影响
Effect of Fushen Decoction(复肾汤)on Thyroid Hormone in Chronic Glomerulo-nephritis of Both Spleen and Kidney-Yang Deficiency Patients
  
DOI:
中文关键词:  复肾汤  慢性肾炎  脾肾阳虚型  甲状腺激素
英文关键词:Fushen Decoction  chronic glomerulo-nephritis  both Spleen and Kidney-Yang Deficiency Syndrome  thyroid hormone
基金项目:
Author NameAffiliation
Han Ming-xiang 安徽中医学院附属医院内科 
Wang Yi-ping 安徽中医学院附属医院内科 
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中文摘要:
      用复肾汤治疗慢性肾炎脾肾阳虚型患者的临床研究发现,治疗前患者存在着甲状腺激素水平降低,表现为血清T3、T4低值,且与脾肾阳虚的证候积分值、BUN、Scr呈显著负相关(P<0.01~0.05),与24h尿蛋白定量无显著相关性(P>0.05)。治疗后,随着病情改善血清T3、T4值明显提高(P<0.01~0.05),但仍低于健康人。与肾炎四味片对照组比较,治疗组T3升高显著(P<0.05),T4无明显差异(P>0.05)。
英文摘要:
      Changes of thyroid hormone level before and after treatment in 45 patients with chronic glomerulo-nephritis were observed. Of which, 23 cases were treated with Fushen Decoction and the other with Shenyan Siwei tablet (肾炎四味片) as control. The results showed: (1) The level of serum T3 and T4 of 45 patients were significantly reduced (P<0.001-0.01). (2) The level of serum T3 and T4 were significantly negative correlated with the value of BUN and Scr and the score of both Spleen and Kidney-Yang Deficiency Syndrome (P<0.01-0.05), but there existed no significant negative correla tion with urinary protein excretion in 24 hours (P>0.05). (3)After treatment with Fushen Decoction, the level of serum T3 and T4 significantly increased (P<0.01-0.05), but no significant change was recorded in control group (P>0.05). (4) Although the level of serum T3 and T4 were raised, they were still lower than those of normal people.
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