| 苏宗泽,何永元,陈高,李志航,杨静,曾荣蓉,李华萍,王裕生,张莉.慢肾灵口服液治疗慢性肾炎临床与实验研究[J].,1993,(5):269-272,259,260 |
| 慢肾灵口服液治疗慢性肾炎临床与实验研究 |
| Clinical and Experimental Study on Effects of Man-Shen-Ling(慢肾灵)Oral Liquid in Treating 100 Cases of Chronic Naphritis |
| |
| DOI： |
| 中文关键词: 慢肾灵口服液 慢性肾炎 免疫性肾炎 正虚邪实 攻补兼施 |
| 英文关键词:Man-Shen-Ling oral liquid chronic nephritis immuno-nephritis |
| 基金项目: |
|
| Hits: 1513 |
| Download times: 1144 |
| 中文摘要: |
| 以中药制剂慢肾灵口服液治疗慢性肾炎100例,显效率69%,总有效率91%;同期采用慢肾宝液对照治疗45例,显效率40%,总有效率66.7%,治疗组疗效明显优于对照组(P<0.001)。动物实验表明,该药对免疫性肾炎模型有治疗作用,并有利尿、消除或减少蛋白尿、增加肾血流量、抗炎、促进纤维蛋白溶解、抗变态反应、调节和促进免疫功能、升高外周血白细胞等作用;急性和长期毒性试验均未发现毒副反应。 |
| 英文摘要: |
| A new Chinese herbal preparation, Man-Shen-Ling (慢肾灵, MSL, consisted of medicinal herbssuch as Astragalus and Rehmannia) in treating 100 cases of chronic nephritis. The effective rate was91% in comparing to 66.7% in the control group, P<0.001. It was markedly effective for proteinuria,hematuria, improvement and recovery of renal functions, edema, anemia, anorexia etc in comparing with the control group. It showed no adverse effects on functions of liver, kidney, heart and GI tract.Animal model of chronic nephitis was established and the effects of MSL were observed. Thelaboratory findings and histopathological investigation on kidney revealed and confirmed that MSLhas therapeutic effects on chronc nephritis. Pharmacodynamically, MSL exhibited effects of anti-allergy, its immuno-suppressive effect corresponded to that of cyclophosphamide, with diuretic,hypotensive, proteinuria eliminating arei-inflammatory, anti-coagulatory, renal blood flow andglomerular filtration enhancing, the excretion of urea-nitrogen, potassium and sodium promotingfunction; in addition, it also could promote and modulate the immunity. Acute and chronic toxicitytests on animal models neither showed toxic, mutagenic, teratogenic nor carcinogenic effects. It isa new preparation of Chinase medicinal herbs in treating chronic nephritis, it is safe and effective. |
| View Full Text View/Add Comment Download reader |
|
|
|
