| 熊丽兰,曹国鸣,吴利华.丹参联合猪苓多糖治疗慢性乙型肝炎疗效观察[J].,1993,(9):533-535,516,517 |
| 丹参联合猪苓多糖治疗慢性乙型肝炎疗效观察 |
| Therapeutic Effect of Combined Therany of Salvia Miltiorrhiza and Polyporus Umbellatus Polysaccharide in Treating Chronic Hepatitis B |
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| DOI： |
| 中文关键词: 丹参 猪苓多糖 慢性乙型肝炎 |
| 英文关键词:Salvia miltiorrhiza Polyporus Umbellatus polysaccharide chronic hepatitis B |
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| 中文摘要: |
| 对乙型肝炎病毒指标阳性伴谷丙转氨酶(ALT)异常的慢性乙型肝炎患者90例,随机分为三组。Ⅰ组30例用丹参联合猪苓多糖;Ⅱ组30例单用猪苓多糖;Ⅲ组单用丹参。疗程均为3个月。治疗结束时ALT复常率Ⅰ组为80.00%,Ⅱ组为40.00%,Ⅲ组为53.33%;HBeAg阴转率分别为56.67%、50.00%和16.67%。追踪观察,于治疗结束后3个月,ALT正常者Ⅰ、Ⅱ和Ⅲ组分别为82、61%、42.68%和59.09%;HBeAg阴转率分别为60.87%、52.38%和22.73%。于停药后9个月ALT正常者为83.33%、43.75%和56.25%;HBeAg阴转率分别为66.67%、56.25%和25.00%。结果提示,丹参与猪苓多糖合用可明显提高疗效,其治疗效果优于单用丹参和单用猪苓多糖者。 |
| 英文摘要: |
| 90 patients of chronic hepatitis B with positive HBV replication markers and abnormality of ALT were randomly allocated to 3 groups. 30 cases were treated with Salvia miltiorrhiza (SM) and Polyporus Umbellatus polysaccharide (PUP) as group Ⅰ, 30 cases were treated with SM solely as group Ⅱ and 30 cases were treated with PUP only as group Ⅲ. By the end of 3 months in the treatment course, normalization rate of ALT were 80.0%, 40.0% and 53.3% and the negative conver-sion rate of HBeAg were 56.7%, 50.0% and 16.7% in the group Ⅰ , Ⅱ and Ⅲ respectively. Follow up for 3 months after the end of therapy, ALT level was normal in 82.6%, 42.7% and 59.1% respectively.HBeAg was negative in 60.9%, 52.4% and 22.7%. Follow up for 9 months after the end of the treatment, ALT was normal in 83.3%, 43.8% and 56.3%. HBeAg was negative in 66.7%, 56.3% and 25.0% respectively. These results showed that combined therapy with SM and PUP might be more potent than SM and PUP therapy alone. |
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