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郭大庆,余江毅,熊宁宁,邹燕勤.132例原发性肾小球疾病载脂蛋白水平与中医辨证分型的关系[J].,1994,(7):409-411
132例原发性肾小球疾病载脂蛋白水平与中医辨证分型的关系
Relationship between Apo-protein in Renal Disease Patients with Diagnosis and TCM Syndrome Differentiation
  
DOI:
中文关键词:  载脂蛋白  辩证分型  脾肾气虚  气阴两虚  肝肾阴虚
英文关键词:apo-protein  Syndrome Differentiation of traditioral chinese medicine  Deficiency of the Spleen Qi and Kidney Qi  Deficiency of Both Qi and Yin  Deficiency of the Liver Yin and Kidney Yin
基金项目:
Author NameAffiliation
Guo Da-qing 江苏省中医院肾病科 
Yu Jiang-yi 江苏省中医院肾病科 
Xiong Ning-ning 江苏省中医院肾病科 
邹燕勤 江苏省中医院肾病科 
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中文摘要:
      分析132例原发性肾小球疾病载脂蛋白水平与中医辩证分型的关系,发现脾肾气虚、气阴两虚、肝肾阴虚证载脂蛋白B(apoB)、apoB/载脂蛋白A-I(apoA-I)均高于正常值,而以脾肾气虚组升高最为明显,且明显高于气阴两虚组和肝肾阴虚组(P<0.05);兼有湿证者apoB、apoB/apoA-I显著高于不兼湿证者(P<0.01),故认为apoB和apoB/apoA-I可作为脾肾气虚及湿证辩证分型的客观指标。
英文摘要:
      The relationship between the level of apo-protein in 132 renal disease patients with diagnosis and TCM Syndrome Differentiation was analysed.The serum apo-protein level of 132 patients group and 135 healthy adults group were monitored with radioimmunodiffusion assay.The patients were divided into three groups.Spleen Qi and Kidney Qi Deficiency(SQKQD),both Qi and Yin Deficiency(QYD),and the Liver Yin and Kidney Yin Deficiency(LYKYD)group.All patients were divided into with-Dampness and without-Dampness group according to their clinical symptoms and signs.Comparison was also made between different groups.Results:Renal diseases including nephrotic syndrome,chronic nephritis,chronic renal failure and patients with SQKQD, QYD,LYKYD,the levels of apo-B and apo-B/apo-A -I were higher than that of normal(P<0.01) in various degree,while the level of apo-A-I.was not changed or lower than the normal.In TCM Syndrome differentiation,apo-B and apo -B/apo-A-I in the SQKQD group were higher than those in QYD and LYKYD group(P<0.05). Moreover,these two values in cases with Dampness were much higher than those without Dampness(P<0.01).Therefore,it is important to treat this secondary abnormality of lipid metabolism for reducing the further deterioration of renal diseases.When primary renal disease was treated,elimination and removal the dampness might reduce the further damage of hyperlipidemia in renal diseases.
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