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孙颂三,袁士琴,唐玉,曲柏林,曲瑞瑶,曾文红.疔毒丸对胃肠平滑肌电活动与胃肠运动效应的影响[J].,1994,(7):424-426
疔毒丸对胃肠平滑肌电活动与胃肠运动效应的影响
Effects of Dingduwan on Electric Activities of Gastrointestinal Smooth Muscle and Effect of Gastrointestinal Motility
  
DOI:
中文关键词:  疔毒丸  胃肠电  胃肠运动  慢波
英文关键词:Dingduwan  gastrointestinal electricity  gastrointestinal motility  slow wave
基金项目:国家中医管理局青年科研基金
Author NameAffiliation
Sun Song-san 首都医学院 
Yuan Shi-qin 北京胸部肿瘤结核病研究所外科 
Tang Yu 首都医学院 
曲柏林 首都医学院 
曲瑞瑶 首都医学院 
曾文红 首都医学院 
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中文摘要:
      采用改进的整体同步记录方法,研究疔毒丸对胃肠平滑肌电活动及胃肠运动效应的影响。大鼠以3.5g/kg灌胃可显著增加胃肠电慢波平均振幅、胃肠运动总振幅、肠电慢波频率和肠运动频率(P<0.05),但对胃电慢波频率和胃运动频率无明显影响(P>0.05)。小鼠以5.2g/kg灌胃可显著促进肠套叠还纳作用。结果显示疔毒丸可增强肠电活动和肠运动,其程度明显大于对胃的作用。
英文摘要:
      Dingduwan(DDW) is a Chinese herbal medicine.Method of modified synchronous recording was used to study the electric activities of gastrointestinal(GI) smooth muscle and the effect of GI motility treated by DDW.A dosage of 3.5g/kg for ingestion in rats markedly increased the average amplitude of GI slow wave,the total amplitude of GI motion,the rateof GI slow wave and intestinal motion(P<0.05),but it had no significant effects on the frequency of gastroelectric slow wave and gastric motility(P<0.05).DDW in the dosage of 5.2g/kg for ingestion markedly promoted the recovery of intestinal intussusception in mice(P>0.05).The results showed that DDW markedly increased the intestinal electricity and motility more than that of stomach.
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