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Author Name	Affiliation
Wang Chang-hong	沈阳军区总医院
Wang Yan-hong	沈阳军区总医院
Zhou Ying	沈阳军区总医院
樊新亚	沈阳军区总医院
高学武	沈阳军区总医院
陈山泉	沈阳军区总医院

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中文摘要:

以益气健脾、清热解毒中药治疗６２例消化性溃疡及糜烂性胃炎，观察治疗前后胃粘膜ＰＧｓ的动态变化。结果显示ＰＧＥ２治疗后与健康人接近（Ｐ＞０．０５），ＰＧＦ１α、６－ｋｅｔｏ－ＰＧＦ１α治疗后显著升高（Ｐ＜０．０１），而ＴＸＢ２较治疗前显著下降（Ｐ＜０．０１）。湿热型ＴＸＢ２较其他型显著升高（Ｐ＜０．０１）。中药对吲哚美辛诱发的大鼠实验性溃疡有明显保护作用，对ＰＧｓ的影响与临床观察一致。

英文摘要:

The PG content were determined in 62 cases with peptic ulcer and erosive gastritis before and after the treatment of Chinese herbal drugs.The value of PGE2,PGFla,6-keto-PGFla and TXB2 were 96.25±28.51, 14.24±13.26, 10.72±9.14 and 16.51±12.24 pg/mg respectively before the treatment and were 121.42±30.02, 18.59±18.40, 18.79±12.61,8.29±6.27 pg/mg respectively after the treatment.6-keto-PGFla was significantly increased(P<0.01), TXB2 was decreased(P<0.01),but there were on significant changes in PGE2 and PGFla.Experimental study also showed that Chinese Herbal drugs played an important role in protecting indomethacine induced ulcer rats.

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