王笑民,郁仁存,王禹堂,饶燮卿,彭晓梅,吉慧敏,冯灵娟.晚期非小细胞肺癌患者气虚血瘀证的研究[J].,1994,(12):724-726 |
晚期非小细胞肺癌患者气虚血瘀证的研究 |
Study on Advanced Non-Small Cell Lung Cancer Patients with Qi Deficiency and Blood Stasis Syndrome |
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DOI: |
中文关键词: 非小细胞肺癌 气虚血瘀证 细胞免疫 血液流变学 |
英文关键词:non-small cell lung cancer Qi deficiency and blood stasis syndrome cell-mediated immunity hemorheology |
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中文摘要: |
本研究对108例晚期非小细胞肺癌患者的中医证型进行了分析,发现60.2%的患者存在气虚血瘀证,痰浊及痰热是气虚血瘀证常见的兼夹证。存在气虚血瘀证的患者免疫功能低下且有血液高凝倾向。研究认为:T细胞亚群、血栓素B2、6-酮-前列腺素F1α、纤维蛋白原及纤维蛋白溶解酶等免疫学及血液流变学指标的异常改变是气虚血瘀证重要的病理生理基础。研究提出晚期非小细胞肺癌的中医治疗应以“益气活血、化痰散结”为主。 |
英文摘要: |
cases of advanced non-small cell lung cancer(NSCLC) with Qi deficiency and blood stasis syndrome(QDBS) had been studied in this paper. It has been found that.(1) QDBS existed commonly in 60.2% of NSCLC patients. (2)QDBS patients had lowered immune function and blood hypercoagulating function, as compared with healthy persons. (3)The abnormal change of immunological indexes such as TC subgroup. TXB2, 6-keto-PGF1α, fibrinogen and plasmin activity as well as hemorheological indices are important pathophysiological manifestation of QDBS. Thus, the principle of supplementing Qi and activating blood circulation combined with reducing phlegm and resolving masses should be emphasized in future research. |
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