| 张暋,梁东辉,李小敏,曾昭龙,钱学贤,尹炳生.冠心病痰瘀辨证分型与血清脂蛋白动态平衡关系的研究[J].,1995,(1):9-12 |
| 冠心病痰瘀辨证分型与血清脂蛋白动态平衡关系的研究 |
| A Study on Relationship between Balance of Serum Lipoprotein and the Phlegm Damp-Blood Stasis Syndrome Differentiation of Coronary Heart Diseases |
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| DOI： |
| 中文关键词: 冠心病 痰瘀辨证分型 冠状动脉造影术 血清脂蛋白谱 |
| 英文关键词:coronary heart disease Phlegm damp-blood stasis Syndrome Differentiation coronary arteriography serum lipoprotein electrophoretogram |
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| 中文摘要: |
| 本研究对７５例确诊为冠心病（ＣＨＤ）的患者行冠状动脉造影术，检测其血清脂蛋白及其亚组分胆固醇含量和血清脂蛋白谱（ＳＬＰＧ）的变化。观察痰瘀辨证各证型与血清脂蛋白动态平衡紊乱的关系，结果表明ＣＨＤ患者ＳＬＰＧ显示血清脂蛋白各组分相对含量异常与痰瘀辨证分型密切相关，在以血清总胆固醇含量（＜５．２０ｍｍｏｌ／Ｌ和＞６．２４ｍｍｏｌ／Ｌ）水平划分的Ａ、Ｂ及Ｃ组的病例中，痰瘀辨证各型分布规律一致，痰瘀型）血瘀型＞气滞血瘀型、痰浊型和无痰瘀型；ＳＬＰＧ与临床情况的符合率８２．７％，高于冠状动脉造影术的６４．０％（Ｐ＜０．０５）。ＳＬＰＧ判别冠状动脉存在病变的敏感性９１．７％及符合率６９．３％，优于其他所测指标（Ｐ＜０．０５～０．０１），为中医诊疗ＣＨＤ提供了新的客观证据。 |
| 英文摘要: |
| 75 patients were divided into A,B and C group.The LDL-C was 2.97±0.67, 4.05±0.38 and 5.25±0.98 mmol/L respectively(P>0.01):but comparing group A or B with the normal group(D),it had no significant difference(p>0.05).An abnormal coronary arteriography(CAG)was found in the group A in 62.1% and the group B in 57.6%(P>0.05),while the group C in 84.6%(P<0.01).There was unusual serum lipoprotein electrophoretogram (SLPG) in group A 75.9%, group B 84.8% and group C 100%,but it had no change in group D(P<0.001).Five types of Syndrome Differentiation about the Phlegm damp and blood stasis(PDBS)could be found in the group A,B and C.The incidence(51.5%～55.2%)and abnormality of the SLPG (66.7%～92.5%) and CAG(68.8%～100%）of PDBS type were the highest among them.82.7% CHD patient’s clinical comprehensive diagnosis was in accordance with the SLPG and that of the CAG were 64.0%.As to the abnormal SLPG,the sensitivity and rate of coincidence of CAG was 91.7% and 69.3%(P<0.05～0.01) respectively.The Syndrome Differentiation of PDBS was.valuable in differentiating CHD.The SLPG is a good criterion for the study of CHD in TCM. |
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