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Author Name	Affiliation
Sun Xiao-xuan	中国中医研究院北京针灸骨伤学院附属医院
Hu Yi-huang	中国中医研究院西苑医院
Bao Xiao-feng	中国中医研究院西苑医院
王秀凤	中国中医研究院西苑医院
刘志云	中国中医研究院西苑医院
徐铭渔	中国中医研究院西苑医院
翁维良	中国中医研究院西苑医院

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中文摘要:

报告了通脉降脂口服液对体外培养的兔主动脉壁中层平滑肌细胞（Ｓｍｏｏｔｈｍｕｓｃｌｅｃｅｌｌ，ＳＭＣ）周期动力学的影响。观察到１．５％、２．０％浓度的通脉降脂口服液随着加药培养时间的延长，可使Ｇ０／Ｇ１期ＳＭＣ所占百分比逐渐减低，Ｓ期ＳＭＣ百分比逐渐升高，而且药物浓度较高时这种作用更为明显。提示通脉降脂口服液对体外培养兔主动脉壁中层ＳＭＣ的增殖有明显的抑制作用。

英文摘要:

The effects of Tongmai Jiangzhi Liquor （TMJZL） on the cell cycle kinetics in smooth muscle cell （SMC） of rabbits’ midlayer of aortic wall was observed. It was showed that TMJZL could extend the time of cell culture, lower the percentage of SMC in G₀/G₁ phase and elevate the percentage of SMC in S phase gradually. The higher the concentration, the stronger the effect. The experiment showed that TMJZL had a marked inhibition of SMC of rabbits’ midlayer of aortic wallcultured in vitro.

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