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Author Name	Affiliation
Chen Ya-xi	重庆医科大学病毒性肝炎研究所
Guo Shu-hua	重庆医科大学病毒性肝炎研究所
Zhang Ding-feng	重庆医科大学病毒性肝炎研究所
陈学华	重庆医科大学病毒性肝炎研究所

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中文摘要:

本文应用重庆麻鸭乙型肝炎动物模型进行了不同产地中草药叶下珠及其联合中药苦参及抗菌药环丙沙星的抗鸭乙型肝炎病毒（ｄｕｃｋｈｅｐａｔｉｔｉｓＢＶｉｒｕｓ，ＤＨＢＶ）疗效初探，连续用药１个月后，结果表明：广西叶下珠、云南叶下珠能使鸭血清中鸭乙型肝炎病毒脱氧核糖核酸（ＤＨＢＶＤＮＡ）滴度下降（Ｐ＜０．０５），而重庆叶下珠无此作用（ｐ＞０．０５）；云南叶下珠停药后有血清ＤＨＢＶＤＮＡ回升现象；广西叶下珠与苦参合用，无明显协同作用，但与环丙沙星合用，似有增强抗病毒的作用（Ｐ＜０．０５）。

英文摘要:

The duck hepatitis B virus model was treated with phyllanthus urinaria of different area and combined with Sopliora flavesceus as well as ciprofloxacin once a day for one month, the results indicated:Guangxi and Yunnan Phyllanthus could lower the serum DHBV DNA significantly(P<0.05),but Chongqing Phyllanthus couldn’t.And the amount of serum DHBV DNA rose a week after stopping of Yunnan Phylianthus.The antiviral effect of Guangxi Phyllanthus combined with ciprofloxacin seems to be strengthened(P<0.05).

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