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丁桂芝,张忠兰,周勇,李榕.补肾健骨胶囊治疗绝经后骨质疏松症疗效分析[J].,1995,(7):392-394
补肾健骨胶囊治疗绝经后骨质疏松症疗效分析
Clinical Study on Effect of Bushen Jiangu Capsule on Postmenopausal Osteoporosis
  
DOI:
中文关键词:  补肾法  骨质疏松症  骨密度
英文关键词:Kidney Tonifying herbs  osteoporosis  bone density
基金项目:国家中医药管理局八·五重点课题
Author NameAffiliation
Ding Gui-zhi 同济医科大学附属协和医院 
Zhang Zhong-lan 北京解放军总医院 
Zhou Yong 武汉市长江医院 
李榕 同济医科大学附属协和医院 
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中文摘要:
      采用随机法观察了补肾健骨胶囊和钙剂治疗绝经后骨质疏松症(各17例)的疗效。结果显示:补肾健骨胶囊治疗3个月后,92.85%的患者腰背疼痛、腰膝酸软等肾虚症状缓解;治疗6个月后,经双能X线骨密度仪(DXA)测定,68.8%的患者L2~4椎体骨密度(BMD)与治疗前比较呈上升趋势(p<0.05).而钙剂对照组BMD却呈下降趋势,组间差异有显著性(P<0.01)。提示补肾健骨胶囊可用于预防和治疗绝经后骨质疏松症。其机理可能与其具有使骨代谢活动增强、骨基质增多(或分解减少)等作用有关。
英文摘要:
      The therapeutic effect of Kidney Tonifying principle and Bushen Jiangu(BSJG) capsule on postmenopausal osteoporosis(17 cases) was observed and compared with calcium treatment group(17 cases) in double-blind method.The result showed that 3 months after treatment with BSJG capsule,the symptoms of 92.85% patients were improved,and 6 months after treatment,the bone density(BD) of lumbar vertebra of 68.8% patients was significantly higher than that of before treatment,but the BD of oontrol group was lower(P<0.05).This suggested that BSJG capsule could prevent and improve postmentopausal osteoporosis.The therapeutic mechanisms probably is improving the bone formation and declining the bone absorption.
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