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张国成,李佐华,沈青,徐瑾,许东亮,王瑞华.清温冲剂对呼吸道病毒感染小儿机体免疫调节作用的研究[J].,1995,(7):408-410
清温冲剂对呼吸道病毒感染小儿机体免疫调节作用的研究
A Study on Effect of Qingwen Granule in Regulating lmmunological Function in Infantile Respiratory Viral Infection
  
DOI:
中文关键词:  清温冲剂  T细胞亚群  γ-干扰素表达细胞
英文关键词:Qingwen Granule  T lymphocyte subsets  interferon γ expression cells
基金项目:
Author NameAffiliation
Zhang Guo-cheng 第四军医大学西京医院儿科 
Li Zuo-hua 第四军医大学西京医院儿科 
Shen Qing 第四军医大学西京医院儿科 
徐瑾 第四军医大学西京医院儿科 
许东亮 第四军医大学西京医院儿科 
王瑞华 第四军医大学西京医院儿科 
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中文摘要:
      采用碱性磷酸酶-抗碱性磷酸酶技术及3H-TdR掺入法,测定T细胞亚群、淋巴细胞转化率及γ-干扰素表达细胞等指标,以评价清温冲剂对呼吸道病毒感染小儿免疫功能的作用。结果显示,清温冲剂组在治疗第4天外周血T3、T4亚群的数值及T4/T8比例与对照组比较无明显差异(P>0.05),但γ-干扰素表达细胞、淋巴细胞刺激指数及分泌性IgA均明显增高,与对照组比较差异显著(P<0.05)。表明清温冲剂能促进和调节机体的免疫功能。
英文摘要:
      To evaluate the effect of Qing-wen Granule(QWG) on immunological function,T lymphocyte subsets and interferon γ(INF-γ) expression cells in peripheral blood mononuclear cells,lymphocyte transformation rate and the level of salivary secretory IgA(sIgA) were determined by alkaline phosphatase antialkaline phosphatase(APAAP) technique or HTdR incorporation with lymphocyte stimulation index(SI) or agar single immunodiffusion in infantile respiratory viral infection.The results showed that the percentage of CD3,CD4,and CD4/CD8 ratio of patients treated with QWG for 3 days were not significantly different in comparing with the control group untreated with QWG(P>0.05),but the values of IFN-γ expression cell,Sl and the level of sIgA were more markedly increased than that of control(p <0.05).It suggested that the QWG could improve and regulate immune function in infantile respiratory viral infection.
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