杨解人,陈国祥,李文明,胡荣华.复方血立停对4种实验性胃溃疡模型的影响[J].,1995,(7):416-418 |
复方血立停对4种实验性胃溃疡模型的影响 |
Effects of Composite Xueliting on Four Gastric Ulcer Models in Rats and Mice |
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DOI: |
中文关键词: 复方血立停 甲氰咪胍 胃溃疡 |
英文关键词:Composite Xueliting cimetidine gastric ulcer |
基金项目:卫生部青年科学研究基金 |
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中文摘要: |
本研究观察了复方血立停对大鼠应激性、组织胺性、水杨酸性和小鼠利血平性胃溃疡模型的影响。结果表明,每天口服复方血立停1次(0.214~0.856g/kg),共5天,对4种溃疡模型的抑制率分别为40%~63%、48%~85%、68%~87%和27%~65%。其中对水杨酸性溃疡模型的作用较为明显。提示复方血立停对实验性胃溃疡具有保护作用。 |
英文摘要: |
Composite Xueliting(CXLT) was found to be an effective anti-ulcer agent in four experimental models in rats and mice,namely,the stress restraint-induced,histamin-induced,salicylic acidinduced and reserpine-induced ulcers.In above-mentioned models,CXLT(0.214~0.856 g/kg,1/d×5,per os) could inhibit gastric ulcer by 40%~63%,48%~85%,68%~87% and 27%~65% respectively.Among these,the salicylic acid-induced ulcer was more markedly inhibited.The result suggested that CXLT had the protective function against the gastric ulcer. |
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