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Author Name	Affiliation
阳晓	湖南中医学院附属第二医院
魏毅	湖南中医学院附属第二医院
何泽云	湖南中医学院附属第二医院
张盛光	湖南中医学院附属第二医院

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中文摘要:

本研究观察了参麦注射液对５／６肾切除大鼠腹膜透析过程中腹腔局部防御功能的影响。结果显示，将参麦注射液加入到腹透液中可显著增加大鼠腹腔中的Ｃ３和ＩｇＧ含量（Ｐ＜０．０５）；对腹腔中的巨噬细胞数量无显著影响，但用药后吞噬指数及吞噬百分率有一定增加趋势，并能减轻腹膜间皮细胞的损伤。提示腹透液中使用参麦注射液对腹腔局部防御功能有增强作用。

英文摘要:

The local defence mechanism of peritoneal cavity plays an important role in preventing peritonitis during peritoneal dialysis. In this experiment, the effect of Shenmai injection (SI) on the defence mechanism was studied in the remnant kidney model. The results showed that the SI which was added into dialysate could significantly increase the concentration of IgG, C3 in peritoneal cavity (P<0.05). There was insignificant change in the number of peritoneal macrophages, but the index and the percentage of phagocytosis had the tendency to increase (P>0. 05). SI also relieved the injury of peritoneal mesothelia cells. All these results suggested that the SI had the ability to augment the peritoneal local defence mechanism.

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