欢迎访问中国中西医结合杂志！

Author Name	Affiliation
刘红菊	同济医科大学附属协和医院呼吸内科
李元桂	同济医科大学附属协和医院呼吸内科
毛文光	同济医科大学附属协和医院呼吸内科

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中文摘要:

采用静脉注射内毒素造成兔急性肺损伤的模型，观察热毒清对其治疗的效果。结果发现热毒清能明显抑制内毒素所引起的兔动脉血ｐＨ值、二氧化碳分压、肺体指数、肺湿干重、肺泡灌洗液内蛋白含量及白细胞总数的升高和动脉血氧分压的下降（Ｐ＜０．０５），并改善病理变化。提示：中药热毒清可阻抑内毒素对兔肺组织的损伤作用，从而阻止了兔的急性肺损伤的发生发展。

英文摘要:

Acute lung injury(ALI) of rabbits was induced by endotoxin and the effects of Reduqing (RDQ) injection on the following indexes were studied. The results showed that the arterial blood PH,PCO2,lung/body index, lung wet/dry weight ratio, the protein and neutrophil contents in bronchoalveolar lavage fluid increased significently together with arterial PO2 marked drop, which were consistent with lung tissue damage, while administration of RDQ simultaneously ameliorated these changes. It is suggested that the Chinese herbal medicine RDQ injection could protect rabbit from the endotoxin-induced ALI.

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