| 杨志波,欧阳恒,李先春.复方二矾浸液治疗手癣的临床与实验研究[J].,1997,(3):150-151 |
| 复方二矾浸液治疗手癣的临床与实验研究 |
| Clinical and Experimental Studies on Composite Divitriol Infusion in Treating Tinea Manum |
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| DOI： |
| 中文关键词: 复方二矾浸液 手癣 中药治疗 |
| 英文关键词:Composite Divitriol Infusion tinea manum Chinese herbal medicine therapy |
| 基金项目: |
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| 中文摘要: |
| 目的：为了验证复方二矾浸液治疗手癣的疗效及机理，本研究对复方二矾浸液治疗手癣进行了临床和实验研究。方法：采用复方二矾浸液浸泡治疗手癣，同时，采用体外抗真菌试验及电镜方法，观察该浸液的临床疗效及抗菌效果。结果。治疗组１３９例中痊愈１０４例（７４．８％），显效２１例（１５．１％），有效１０例（７．２％），无效４例（２．９％）；愈显率（痊愈＋显效）８９．９％；与采用鹅掌风药液治疗的对照组愈显率（７５．３％）比较，有显著性差异（Ｘ２＞１２．８４，Ｐ＜０．００５）。体外抑制真菌试验表明，复方二矾浸液对红色毛癣菌、石膏样毛癣菌、石膏样小孢子菌的最小抑制浓度分别为０．２５％、０．５％、Ｏ．５％。经复方二矾浸液处理后的红色毛癣菌，电镜观察发现，菌丝体粗糙、变形、大分生孢子变小。结论：临床和实验提示复方二矾浸液是治疗手癣有效的药物。 |
| 英文摘要: |
| To investigate the effect of Composite Divitriol Infusion (CDI) in treating tinea manum and studying its antimycotic action. Methods: CDI was used to treat 139 patients with tinea manum. The experimental study in vivo was done, scanning electron microscopy (SEM)was used to observe the therapeutical effect of CDI. Results: One hundred and four cases among the 139 patients were cured, 21 were markedly effective, 10 improved and 4 ineffective, the effective rate being 89. 9%. Between CDI group and the control group, there was a very significant difference (X2 >12. 84, P<0.005) . The antimycotic action of CDI was studied in vitro. Its minimum inhibitory concentrations(MIC) of CDI were about 0. 25% for Trichophyton rubrum, and 0, 5% for Trichophyton gypseum and Microsporum gypseum. Trichophyton rubrum immersed with CDI show that the mycelia became roughened, deformed and macroconidum became smaller under SEM. Conclusion:CDI is valuable in treating tinea manum. |
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