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吴家宽,顾仁樾,肖沪生,汪长根,何燕.银蒺胶囊改善心绞痛(血瘀证)患者左心室收缩功能的临床研究[J].,1997,(4):210-212
银蒺胶囊改善心绞痛(血瘀证)患者左心室收缩功能的临床研究
Clinical Study of Effect of Yinji Capsule on Left Ventricular Systolic Function of Angina Pectoris Patients with Blood Stasis Syndrome
  
DOI:
中文关键词:  银蒺胶囊  左心室收缩功能  冠心病心绞痛  三维超声心动图
英文关键词:Yinji Capsule  ventricular systolic function  coronary heart disease  three dimensional echocardiography
基金项目:
Author NameAffiliation
吴家宽  
顾仁樾  
肖沪生  
汪长根  
何燕  
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中文摘要:
      目的:为探讨银蒺胶囊改善心绞痛患者左心室收缩功能的机理。方法:用三维超声心动图检查了28例冠心病心绞痛(血瘀证)患者服用银蒺胶囊前后左心室收缩功能的变化。结果:临床症状总有效率为85.7%;心功能变化:左心室射血分数升高(治疗前为45.0±4.9%,治疗后为48.2±3.5%,P<0.05);其中收缩早期和晚期射血分数均升高(治疗前分别为22.6±2.1%和8.3±1.2%,治疗后分别为28.1±3.0%和10.3±0.9%,P<0.01和P<0.05),左心室节段收缩率<5%的心肌范围显著降低(P<0.01)。结论:银蒺胶囊可以改善心绞痛(血瘀证)患者左心室收缩早、晚期收缩功能,而且主要提高低收缩率区心肌收缩功能。
英文摘要:
      To explore the Yinji Capsule (YJC) in improving the left ventricular systolic function of angina pectoris patients with Blood Stasis Syndrome. Methods: The systolic function of left ventricle (LV)in cardiac cycle of 28 angina pectoris patients with Blood Stasis Syndrome was examined with three-dimensional echocardiograph (3-DE) before and after treatment with YJC. Results: The total symptomatic effective rate was 85. 7%. The changes of LV systolic function were those: left ventricle ejection fraction(LVEF)increased from 45. 0± 4. 9 % to 48. 2± 3. 5% (P<0. 05):EF on early stage and late stage increased from 22. 6± 2. 1 %, 8. 3± 1. 2% to 28. 1 ± 3. 0% and 10. 3±0. 9 % respectively (P< 0. 01, P< 0. 05 ), myocardial region with segment systole (SS) < 5 % decreased significantly (P<0. 01 ). Conclusion: YJC could improve LV systolic function on early stage and late stage in cardiac cycles,and mainly improve the systolic function of the region with low SS of LV.
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