| 沈迪,沈霖,王爱莲,刘仲萍,杨锐,魏文宁.消瘀止血片治疗未明原因多部位出血伴血小板聚集缺陷104例临床观察[J].,1997,(5):280-282 |
| 消瘀止血片治疗未明原因多部位出血伴血小板聚集缺陷104例临床观察 |
| Clinical Observation on effect of Xiaoyu Zhixue Tablet on 104 Patients with Idiopathic Multifocal Bleeding and Platelet Aggregation Defect |
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| DOI： |
| 中文关键词: 多部位出血 血小板聚集缺陷 消瘀止血片 |
| 英文关键词:multifocal bleeding platelet aggregation defect Xiaoyu Zhixue Tablet |
| 基金项目:国家自然科学基金 |
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| 中文摘要: |
| 目的：探讨消瘀止血片药理作用的机制。方法：应用益气祛瘀药制成消瘀止血片，共治疗１０４例未明原因多部位出血伴血小板聚集缺陷者。本研究分为２组：中药组１０４例用消瘀止血片治疗，对照组８４例用维生素Ｃ、Ｋ、Ｐ，安络血和（或）人工月经治疗，两组均治疗４个月以上。结果：中药组的止血疗效为９２．３％，对照组为２７．４％（ｘ２＝２０．６３，Ｐ＜０．００５）；各组治疗６个月后的血小板聚集恢复率：中药组为６９．２％，对照组仅１．８％，两组间有显著性差异（Ｘ２＝３１．１９，Ｐ＜０．００５）。结论：消瘀止血片可能是通过调节血管和血小板的生理功能，使其在临床上达到很好的止血和恢复血小板功能的效果。 |
| 英文摘要: |
| Objective: To explore the effect and pharmacological mechanism of Xiaoyu Zhixue Tablet (XZT). Methods: The XZT mainly composed of Chinese medicinal herbs to replenishing Qi and removing stasis was used to treat patients with idiopathic multifocal bleeding and platelet aggregation defect. Patients were divided into 2 groups. The TCM group (104 cases) treated with XZT, and the control group (84 cases) treated with vitamins C, K and P, adrenosin and (or) artificial menstruation, for at least 4 months. Results: The hemostatic effective rate was 92. 3% in TCM group and 27. 4 % in control group (P<0. 005 ), the recovery rate of platelet aggregation after 6 months therapy was 69. 2% and only 1. 8% respectively. The difference between two groups was very significant (p<0.005). Conclusion: XZT could regulate the physiological functions of blood-vessel and platelet to realize the hemostatic action and platelet aggregation. |
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